Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D. P. Rossignol"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:181-186
The preparation and SAR of a series of batrachotoxin partial structures that antagonize binding and activity of batrachotoxin are reported in this communication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e014612560979edcdae4003ca78553
https://doi.org/10.1016/s0960-894x(96)00596-3
https://doi.org/10.1016/s0960-894x(96)00596-3
Autor:
Hector R. Wong, A R Steve, Bruce R. Pitt, Grace L. Su, Stewart C. Wang, D P Rossignol, Timothy R. Billiar
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 12:449-454
Lipopolysaccharide (LPS)-binding protein (LBP) binds with high affinity to LPS, and the LBP-LPS complex enhances cellular inflammatory responses to LPS. Although it is present in normal serum, LBP is also induced as part of the acute phase response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554f023b986aee10edcfebc56f24019a
https://doi.org/10.1165/ajrcmb.12.4.7695925
https://doi.org/10.1165/ajrcmb.12.4.7695925
Publikováno v:
ChemInform. 28
The preparation and SAR of a series of batrachotoxin partial structures that antagonize binding and activity of batrachotoxin are reported in this communication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a73249fdd4c8901d505a863c7542895
https://doi.org/10.1002/chin.199720189
https://doi.org/10.1002/chin.199720189
Autor:
T, Kawata, J R, Bristol, D P, Rossignol, J R, Rose, S, Kobayashi, H, Yokohama, A, Ishibashi, W J, Christ, K, Katayama, I, Yamatsu, Y, Kishi
Publikováno v:
British journal of pharmacology. 127(4)
1. The major pathological responses to Gram-negative bacterial sepsis are triggered by endotoxin or lipopolysaccharide. As endotoxin is shed from the bacterial outer membrane, it induces immunological responses that lead to release of a variety of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8424058107a931cacf166bcc701c60c
https://pubmed.ncbi.nlm.nih.gov/10433491
https://pubmed.ncbi.nlm.nih.gov/10433491
Publikováno v:
Infection and immunity. 63(3)
Lipid A from the photosynthetic bacterium Rhodobacter sphaeroides (RSLA) has been previously shown to antagonize many of the effects of endotoxins from more pathogenic gram-negative bacteria. We have reported on the synthesis of the proposed structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bced05e9aac603119eedad4e1e10b35b
https://pubmed.ncbi.nlm.nih.gov/7868254
https://pubmed.ncbi.nlm.nih.gov/7868254
Autor:
T, Kawata, J R, Bristol, J R, Rose, D P, Rossignol, W J, Christ, O, Asano, G R, Dubuc, W E, Gavin, L D, Hawkins, Y, Kishi
Publikováno v:
Progress in clinical and biological research. 392
Lipid As from non-toxic bacteria such as Rhodobacter capsulatus and Rhodobacter sphaeroides have been shown to antagonize the immunostimulatory effects of lipid A and LPS from pathogenic bacteria. We have biologically characterized a series of synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53d7c4abd31729a7d7272fb26eb61010
https://pubmed.ncbi.nlm.nih.gov/8524958
https://pubmed.ncbi.nlm.nih.gov/8524958
Autor:
S C, Wang, D P, Rossignol, W J, Christ, D A, Geller, P D, Freeswick, N L, Thai, G L, Su, R L, Simmons
Publikováno v:
Surgery. 116(2)
Many of the physiologic derangements resulting in septic shock are caused by inflammatory mediators such as nitric oxide (NO) and cytokines produced in response to bacterial endotoxin or, more specifically, lipopolysaccharide. The recent development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f399cef8b1a88a176c63d0a23a6e4d86
https://pubmed.ncbi.nlm.nih.gov/7482285
https://pubmed.ncbi.nlm.nih.gov/7482285
Autor:
Michael B. Sawyer, I. Krivelevich, D. P. Rossignol, C. S. Rocha Lima, Anthony B. El-Khoueiry, H. J. Lenz, J. Fan, Syma Iqbal
Publikováno v:
Journal of Clinical Oncology. 28:3537-3537
3537 Background: In vitro,E7820, inhibits α2-integrin expression, endothelial cell proliferation, and vascular tube formation. In colorectal cancer xenograft models, the combination of E7820 and ce...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba21074b7a318001e8fce8f8682d936
https://doi.org/10.1200/jco.2010.28.15_suppl.3537
https://doi.org/10.1200/jco.2010.28.15_suppl.3537
Autor:
C. Okereke, Anthony B. El-Khoueiry, T. Goldberg, P. Conti, K. Feit, D. P. Rossignol, I. Krivelevich, Syma Iqbal, H. J. Lenz
Publikováno v:
Journal of Clinical Oncology. 26:3568-3568
3568 Background: In vitro, E7820 inhibits α2-integrin expression, endothelial cell proliferation and vascular tube formation. The maximum tolerated dose (MTD) of E7820 as a single agent is 100mg/da...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d86cbfce17f2d6f110a87f29fa8ef5
https://doi.org/10.1200/jco.2008.26.15_suppl.3568
https://doi.org/10.1200/jco.2008.26.15_suppl.3568
Autor:
J C Vary, D P Rossignol
Publikováno v:
Journal of Bacteriology. 138:431-441
The mechanism by which L-proline triggers germination in Bacillus megaterium QM B1551 spores was investigated. First, brief exposure of spores to L-proline, followed by dilution, was sufficient to trigger germination. Once germination was triggered,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c4ab46137f3de2e52051e6bacf4f23
https://doi.org/10.1128/jb.138.2.431-441.1979
https://doi.org/10.1128/jb.138.2.431-441.1979