Výsledky vyhledávání - "D. P. Metzgar"

SYSTEMIC REACTIONS TO INFLUENZA B VACCINE

Autor: D P Metzgar, A N DeSanctis, Jr. Jack M. Gwaltney, J O Hendley

Publikováno v: American Journal of Epidemiology. 105:252-260

Standard whole virus influenza vaccine (1974-1976) containing 700 chicken cell agglutinating (CCA) units of type A (Port Chalmers/1/75) or Port Chalmers plus Scotland/840/74) and 500 units of type B (HK/8/73) antigens was found to produce excessive s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a177f0e7259899791eeb7c21887a8fd
https://doi.org/10.1093/oxfordjournals.aje.a112381

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Adenovirus Soluble Antigen Vaccine Studies I. Preparation and Testing of Adenovirus Type 5 Soluble Antigen Vaccines

Autor: W. J. Thomas, D. P. Metzgar, C. S. Insalaco, A. N. Desanctis, J. M. Beiler

Publikováno v: Experimental Biology and Medicine. 128:679-683

SummaryA monovalent type 5 soluble antigen vaccine was prepared by methanol concentration, alkaline treatment, and brushite purification from virus propagated in WI-38 (diploid) cells. The vaccine was water-clear, contained minimal protein, and evoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c33e74344b1d1ac1ef905baa9d24ac
https://doi.org/10.3181/00379727-128-33098

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New Metabolizable Immunologic Adjuvant for Human Use. 4. Development of Highly Purified Influenza Virus Vaccine in Adjuvant 65

Autor: D. P. Metzgar, Alfred A. Tytell, A. F. Woodhour, Maurice R. Hilleman, Lampson Gp, R. A. Machlowittz

Publikováno v: Experimental Biology and Medicine. 123:778-782

SummaryThe development and animal testing of a bivalent influenza virus vaccine in immunologic adjuvant 65 employing a new highly purified viral antigen is described. The enhancement of serologic response to the highly purified viral antigen in adjuv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f4ca1ab7639c011b4acf7d1182d2dd
https://doi.org/10.3181/00379727-123-31601

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New Metabolizable Immunologic Adjuvant for Human Use. I. Development and Animal Immune Response

Autor: D. P. Metzgar, T. B. Stim, Maurice R. Hilleman, A. F. Woodhour, Alfred A. Tytell

Publikováno v: Experimental Biology and Medicine. 116:516-523

SummaryA new immunologic adjuvant, adjuvant 65, is described and the results of extensive tests of polyvalent influenza virus vaccine in the adjuvant are presented. The vaccine consists of a water-in-oil emulsion in which the adjuvant portion consist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2739a2e104a1b684c07ce01c5c61357a
https://doi.org/10.3181/00379727-116-29295

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Separation of Growth Promoting Activity from Horse Serum by Dialysis

Autor: D. P. Metzgar, Merwin Moskowitz

Publikováno v: Experimental Biology and Medicine. 104:363-365

SummaryA method for separation of a fraction from horse serum which does not react in tests for protein and which is capable of substituting for whole serum in tissue culture medium has been described. When this fraction was used as a supplement in s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b66eb48d3eee8c481d566593b0719897
https://doi.org/10.3181/00379727-104-25838

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Further studies on the neonatal ferret model of infection and immunity to and attenuation of human parainfluenza viruses

Autor: C C, Mascoli, T A, Gower, F A, Capilupo, D P, Metzgar

Publikováno v: Developments in biological standardization. 33

Earlier we reported on the susceptibility via the intranasal route of inoculation of newborn ferrets to infection by wild and serially egg passaged parainfluenza type 3 virus. The wild type consistently induced fatal infection whereas with serial egg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::380faf0fabf88feab9eb8a898f72bab5
https://pubmed.ncbi.nlm.nih.gov/182598

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An animal model for studying infection and immunity to and attenuation of human parainfluenza viruses

Autor: C C, Mascoli, D P, Metzgar, E J, Larson, A A, Fuscaldo, T A, Gower

Publikováno v: Developments in biological standardization. 28

Neonatal ferrets were found to be highly via the intranasal route of inoculation to infection with wild type isolates of parainfluenza viruses. Wild type infection consistently resulted in deaths of these animals in 48 to 72 hours. Autopsy and histop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::097f99d0e092bf46aef286dd8f9456b5
https://pubmed.ncbi.nlm.nih.gov/165121

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