Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D. O. Zharkov"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 4, Pp 341-348 (2022)
One of the main mechanisms of epigenetic regulation in higher eukaryotes is based on the methylation of cytosine at the C5 position with the formation of 5-methylcytosine (mC), which is further recognized by regulatory proteins. In mammals, methylati
Externí odkaz:
https://doaj.org/article/c87bd574bf794791ad85b936d05920be
Autor:
A. V. Yudkina, E. A. Kovalenko, A. V. Endutkin, E. P. Panferova, A. A. Kirilenko, A. A. Kokhanenko, D. O. Zharkov
Publikováno v:
Molecular Biology. 57:312-319
Publikováno v:
Molecular Biology. 57:258-271
Abstract The CRISPR/Cas9 system, which was discovered recently, utilizes nucleases targeted by sequence complementarity and is originally intended to protect bacteria from foreign genetic elements. The system provided a convenient tool for manipulati
Autor:
A. V. Endutkin, D. O. Zharkov
Publikováno v:
Molecular Biology. 55:193-210
Autor:
E. S. Shilkin, D. V. Petrova, V. A. Poltorachenko, E. O. Boldinova, D. O. Zharkov, A. V. Makarova
Publikováno v:
Molecular Biology. 55:267-272
Autor:
M. A. Dymova, A. V. Endutkin, V. V. Polunovsky, A. I. Zakabunin, E. A. Khrapov, N. A. Torgasheva, A. V. Yudkina, G. V. Mechetin, M. L. Filipenko, D. O. Zharkov
Publikováno v:
Molecular Biology. 55:225-233
Autor:
S. K. Yuyukina, D. O. Zharkov
Publikováno v:
Herald of the Russian Academy of Sciences. 92(4)
The COVID-19 pandemic has made it necessary to create antivirals active against the SARS-CoV-2 coronavirus. One of the widely used strategies to fight off viral infections is the use of modified nucleoside analogues that inhibit viral replication by
Publikováno v:
Vavilovskii zhurnal genetiki i selektsii. 26(4)
One of the main mechanisms of epigenetic regulation in higher eukaryotes is based on the methylation of cytosine at the C5 position with the formation of 5-methylcytosine (mC), which is further recognized by regulatory proteins. In mammals, methylati
Autor:
A V, Endutkin, D O, Zharkov
Publikováno v:
Molekuliarnaia biologiia. 55(2)
The GO system is part of the DNA base excision repair pathway and is required for the error-free repair of 8-oxoguanine (oxoG), one of the most common oxidative DNA lesions. Due to the ability of oxoG to form oxoG:A mispairs, this base is highly muta
Autor:
M A, Dymova, A V, Endutkin, V V, Polunovsky, A I, Zakabunin, E A, Khrapov, N A, Torgasheva, A V, Yudkina, G V, Mechetin, M L, Filipenko, D O, Zharkov
Publikováno v:
Molekuliarnaia biologiia. 55(2)
Mycobacterium tuberculosis cells contain two apurinic/apyrimidinic (AP) endonucleases, endonuclease IV (MtbEnd) and exonuclease III (MtbXthA), the former playing a dominant role in protecting mycobacterial DNA from oxidative stress. Mycobacterial end