Zobrazeno 1 - 4
of 4
pro vyhledávání: '"D. O. Somers"'
Sulfonamides were amongst the first clinically useful antibacterial agents to be discovered. The identification of sulfanilamide as the active component of the dye Prontosil rubrum led to the synthesis of clinically useful analogues. Today sulfametho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb5ca4005a12bd847ed25ee48a3d51f
https://doi.org/10.1038/nsb0697-490
https://doi.org/10.1038/nsb0697-490
Autor:
David L. Scott, D. O. Somers, J. Rosemond, David K. Stammers, P.K. Bryant, Aniruddha Achari, J.N. Champness
Publikováno v:
FEBS letters. 456(1)
The X-ray crystal structure of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase (PPPK) in a ternary complex with ATP and a pterin analogue has been solved to 2.0 A resolution, giving, for the first time, detailed information of the PPPK/ATP intermo
Autor:
Elspeth F. Garman, Robert Esnouf, David K. Stammers, D. O. Somers, David I. Stuart, E Y Jones, C. Ross, Jingshan Ren
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 54(Pt 5)
A crystal form of HIV-1 reverse transcriptase (RT) complexed with inhibitors showed diffraction to a high-resolution limit of 3.7 A. Instability in the unit-cell dimensions of these crystals was observed during soaking experiments, but the range of t
Autor:
O. Matsumoto, R. Griest, Brendan Larder, David Phillips, Denise M. Lowe, D. O. Somers, C. Ross, Garry L. Taylor, David K. Stammers, Margaret Tisdale, Kenneth L. Powell, Dorothy J. M. Purifoy, E Y Jones, Elspeth F. Garman, David I. Stuart, Graham Darby
Publikováno v:
JOURNAL OF CRYSTAL GROWTH. 126(2-3)
Extensive studies on the crystallization of HIV-1 reverse transcriptase (RT) have yielded several crystal forms, two of which show diffraction to minimum Bragg spacings of 6 A or better. Type 1 crystals belong to the space group P2 1 2 1 2 1 with uni