Zobrazeno 1 - 10
of 189
pro vyhledávání: '"D. O'Kelly"'
Autor:
Chathurika Henpita, Rajesh Vyas, Chastity L. Healy, Tra L. Kieu, Aditi U. Gurkar, Matthew J. Yousefzadeh, Yuxiang Cui, Aiping Lu, Luise A. Angelini, Ryan D. O'Kelly, Sara J. McGowan, Sanjay Chandrasekhar, Rebecca R. Vanderpool, Danielle Hennessy‐Wack, Mark A. Ross, Timothy N. Bachman, Charles McTiernan, Smitha P. S. Pillai, Warren Ladiges, Mitra Lavasani, Johnny Huard, Donna Beer‐Stolz, Claudette M. St. Croix, Simon C. Watkins, Paul D. Robbins, Ana L. Mora, Eric E. Kelley, Yinsheng Wang, Timothy D. O'Connell, Laura J. Niedernhofer
Publikováno v:
Aging Cell. 22
Autor:
Arjun Kanuri, MD, MBA, Neil D. O’Kelly, MD, John Shuck, MD, Paul Kim, DPM, Karen K. Evans, MD, Christopher E. Attinger, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 9, p e1864 (2018)
Background:. Local muscle flaps are a reconstructive option for wound coverage in the distal lower extremity, particularly in high-risk patients who are poor candidates for free tissue transfer. At our institution, chronic and infected wounds are man
Externí odkaz:
https://doaj.org/article/48ea7475f8bc447a895687b9485a999a
Autor:
Ryan D. O’Kelly, Dong Wang, Tokio Sano, Warren C. Ladiges, Yinsheng Wang, Kyoo a. Lee, Johnny Huard, Sara J. McGowan, Ingunn M. Stromnes, Rafael R. Flores, Sara E. Lewis, Laura J. Niedernhofer, Robert W. Brooks, Aiping Lu, Zoe C. Schmiechen, Michael P. Bank, Nam Vo, Jenna Klug, Adam L. Burrack, Luise A. Angelini, Nicholas F. LaRusso, Qing Dong, Paul D. Robbins, Matthew J. Yousefzadeh, Christy E. Trussoni, Christin E. Burd, Smitha P. S. Pillai, Jonathan I. Kato, Yi Zhu, Yuxiang Cui, Erin A. Wade, Collin A. McGuckian, Eric E. Kelley
Publikováno v:
Nature
Ageing of the immune system, or immunosenescence, contributes to the morbidity and mortality of the elderly(1,2). To define the contribution of immune system ageing to organism ageing, here we selectively deleted Ercc1, which encodes a crucial DNA re
Autor:
Zaira Aversa, Yousin Suh, Ayumi Sakamoto, Theodore M. Kamenecka, Johnny Huard, Matthew J. Yousefzadeh, Paul D. Robbins, Luise Angelini, Lei Zhang, Sara J. McGowan, Jing Zhao, Laura J. Niedernhofer, Xiaodong Mu, Nathan K. LeBrasseur, Ryan D. O’Kelly
Publikováno v:
Aging Cell
Constitutive NF‐κB activation is associated with cellular senescence and stem cell dysfunction and rare variants in NF‐κB family members are enriched in centenarians. We recently identified a novel small molecule (SR12343) that inhibits IKK/NF
Autor:
Utkarsh Tripathi, Mark Pierson, Paul D. Robbins, Nino Giorgadze, James L. Kirkland, David B. Allison, Tamara Tchkonia, Stephen C. Jameson, Sara E. Hamilton, Larissa G.P. Langhi Prata, Christina L. Inman, Stephanie H. Cholensky, Lei Zhang, Elizabeth J. Atkinson, Ming Li, Yi Zhu, Christina D. Camell, Jair Machado Espindola-Netto, Laura J. Niedernhofer, Tamar Pirtskhalava, Matthew A. Huggins, Alexander Meves, Matthew J. Yousefzadeh, Sundeep Khosla, Keisuke Ejima, Sergio E. Chiarella, Y. S. Prakash, M. Gerard O'Sullivan, Ryan D. O’Kelly, Nathan K. LeBrasseur, Timothy W. Carlson, Pengcheng Xun, Kurt O. Johnson, Ailing Xue
Publikováno v:
Science (New York, N.Y.)
INTRODUCTION: The COVID-19 pandemic revealed enhanced vulnerability of the elderly and chronically ill to adverse outcomes upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Senescence is a cell fate elicited by cellular str
Autor:
Patrick D. O'Kelly-Lynch, Paul D. Gallagher, Paul Leahy, Eamon McKeogh, Alistair G.L. Borthwick
Publikováno v:
O’Kelly-Lynch, P J, Gallagher, P D, Borthwick, A, McKeogh, E J & Leahy, P G 2020, ' Offshore Conversion of Wind Power to Gaseous Fuels: Feasibility Study in a Depleted Gas Field ', Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, vol. 234, no. 2, pp. 226-236 . https://doi.org/10.1177/0957650919851001
A proof-of-concept study is presented of a Power-to-Gas system that is located fully offshore. This paper analyses how such a system would perform if based at the depleted Kinsale Gas Field in the Celtic Sea Basin off the south coast of Ireland. An o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad768749c2d979896f082362e56eeaf
https://hdl.handle.net/20.500.11820/6bd53da0-51f4-4f4c-beda-0f0f17237f9e
https://hdl.handle.net/20.500.11820/6bd53da0-51f4-4f4c-beda-0f0f17237f9e
Autor:
Cecilia Pastorino, Jordi Molina, Cristina Grange, Paul D. Robbins, Benedetta Bussolati, Elli Papadimitriou, Ryan D. O’Kelly, Laura J. Niedernhofer, Veronica Dimuccio, Giovanni Camussi
Publikováno v:
Molecular Therapy
Acute kidney injury, defined by a rapid deterioration of renal function, is a common complication in hospitalized patients. Among the recent therapeutic options, the use of extracellular vesicles (EVs) is considered a promising strategy. Here we prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e726d5aaafe2fd3a659f6d02da884a3
http://hdl.handle.net/2318/1726934
http://hdl.handle.net/2318/1726934
Autor:
Heather Nick, Nam Vo, Enrico Pola, Ryan D. O’Kelly, Aditi U. Gurkar, Laura J. Niedernhofer, Lana Corbo, Xuesen Li, Johnny Huard, Sara J. McGowan, Jing Zhao, Smitha P.S. Pilla, Paul D. Robbins, Christina Bukata, Lei Zhang, Aiping Lu, Matthew J. Yousefzadeh, Hongshuai Li, Luise Angelini, Alex C. Scibetta, Debora Colangelo, Warren C. Ladiges, Tokio Sano, Yingchao Han
Publikováno v:
Aging (Albany NY)
NF-κB is a transcription factor activated in response to inflammatory, genotoxic and oxidative stress and important for driving senescence and aging. Ataxia-telangiectasia mutated (ATM) kinase, a core component of DNA damage response signaling, acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477e00d470cc3399b1c41bfe8585e110
http://hdl.handle.net/10807/154814
http://hdl.handle.net/10807/154814
Publikováno v:
Renewable and Sustainable Energy Reviews. 119:109583
The integration of offshore wind and wave or tidal energy devices could be an important step towards realizing the economic competitiveness of less advanced renewable energy technologies. The foundations of such integrated solutions require a major s
Publikováno v:
Proceedings of the Nutrition Society. 77