EVALUATION OF DIFFERENT SOURCES OF OXIDATIVE STRESS ON STROKE-SUSCEPTIBILITY IN SHRSP

Autor: Hiroki Ohara, Toru Nabika, M. Ferdaus, Koichi Fujikawa, Hasan M. Zahid, D. Ngarashi

Publikováno v: Journal of Hypertension. 37:e301

Objective:Oxidative stress has been implicated in the pathophysiology of cerebral stroke in SHRSP. As several systems contribute to the regulation of oxidative stress, we evaluated the significance of four systems, i.e., NADPH oxidases (NOXs), xanthi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b889581628dcab5f16410528a00a3cb
https://doi.org/10.1097/01.hjh.0000573804.77613.3f

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Pathophysiological significance of Stim1 mutation in sympathetic response to stress and cardiovascular phenotypes in SHRSP/Izm: In vivo evaluation by creation of a novel gene knock-in rat using CRISPR/Cas9.

Autor: Odongoo B; Department of Functional Pathology, Faculty of Medicine, Shimane University , Izumo, Japan., Ohara H; Department of Functional Pathology, Faculty of Medicine, Shimane University , Izumo, Japan., Ngarashi D; Department of Functional Pathology, Faculty of Medicine, Shimane University , Izumo, Japan.; Department of Physiology, School of Medicine, Muhimbili University of Health and Allied Sciences , Dar Es Salaam, Tanzania., Kaneko T; Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University , Kyoto, Japan.; Laboratory of Animal Reproduction and Development, Faculty of Science and Engineering, Iwate University , Morioka, Japan., Kunihiro Y; Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University , Kyoto, Japan.; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University , Osaka, Japan., Mashimo T; Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University , Kyoto, Japan.; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University , Osaka, Japan.; Laboratory Animal Research Center, the Institute of Medical Science, The University of Tokyo , Tokyo, Japan., Nabika T; Department of Functional Pathology, Faculty of Medicine, Shimane University , Izumo, Japan.

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2021 Jan 02; Vol. 43 (1), pp. 34-41. Date of Electronic Publication: 2020 Jul 23.