Zobrazeno 1 - 10
of 90
pro vyhledávání: '"D. Neville Jones"'
Publikováno v:
Tetrahedron: Asymmetry. 10:4129-4142
The synthesis of (+)-trans-2-mercaptocyclohexanol and (-)-trans-2-mercaptocyclohexanol was described. Ring opening of cyclohexene oxide with (-)-4-methoxybenzyl-3(R)-nopanethiol followed by oxidn. gives two readily separable diastereomeric sulfoxides
Publikováno v:
Tetrahedron. 55:9933-9946
The allylic sulphoxides1b and1e reacted with 1-pyrrolidinylcyclohexene and 2-ethoxycarbonyl cyclopentanone to yield the 2-substituted keto-sulphoxides10 and14 respectively, which on reduction followed by oxidation yielded in each case a mixture ofcis
Autor:
Michael R. Peel, Harry Adams, D. Neville Jones, Richard Bell, Nicholas C. O. Tomkinson, James C. Anderson
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3967-3974
The mild and efficient generation of benzenesulfenic acid by the thermolysis of ethyl 2-ethoxycarbonyl-3-(phenylsulfinyl)butanoate 8 in refluxing dichloromethane, and its in situ trapping with (E)- and (Z)-1-methoxybut-2-en-3-yne to form (E)-1-methox
Autor:
Mark A. Collins, D. Neville Jones
Publikováno v:
Tetrahedron. 52:8795-8806
Efficient synthesis of 6-endo-methyl substituted bicyclo[2.2.1]heptane derivatives formed via completely diastereoselective intramolecular Michael addition reactions of vinyl sulfones, derived from allyl sulfones and cyclopentenones, are described.
Autor:
D. Neville Jones, Mark A. Collins
Publikováno v:
Tetrahedron Letters. 36:4467-4470
A short, stereoselective synthesis of estradiol, and its 6,6-dimethyl analogue, was accomplished from non-steroidal starting materials. A key feature was the use of a benzo[b]thiophene unit to effect (i) the stereoselective formation of the required
Publikováno v:
Tetrahedron: Asymmetry. 5:805-808
Enantiopure 1-methoxy-3-(1-phenyl- and 2-phenyl-2-hydroxyethylsulfinyl)-1,3-butadienes were prepared from ethyl mandelate. Diels-Alder reactions with methyl acrylate proceeded with complete regioselectivity and high diastereoselectivity.
Publikováno v:
Tetrahedron Letters. 34:6481-6484
Cycloadditions of methyl acrylate to (R S )- and (S S )-(E)-3-[(1S)-isobornyl-10-sulfinyl]-1-methoxy-buta-1,3-dienes in dichloromethane, catalysed by lithium perchlorate or zinc chloride, proceeded with complete regioselectivity and high stereoselect
Publikováno v:
Tetrahedron Letters. 34:8553-8556
Anionic species formed by treatment of vinyl sulfones with hydridoaluminates were trapped intramolecularly by esters to provide six- and seven-membered cyclic ketosulfones, e.g. I (R = Me, H, Ar = p-tolyl) and II, exemplified by the stereoselective c
Autor:
D. Neville Jones, Nicholas C. O. Tomkinson, Wood William Wakefield, Steven Swallow, Mark W. J. Maybury
Publikováno v:
Tetrahedron Letters. 42:2193-2195
A new approach to the synthesis of optically pure trans-perhydroazulenes and trans-hydrindanes using a homochiral sulfoxide auxiliary to control both chemical reactivity and enantioselectivity is described.
Autor:
Nicholas C. O. Tomkinson, Michael R. Peel, James C. Anderson, D. Neville Jones, Richard Bell, Harry Adams
Publikováno v:
ChemInform. 30
The mild and efficient generation of benzenesulfenic acid by the thermolysis of ethyl 2-ethoxycarbonyl-3-(phenylsulfinyl)butanoate 8 in refluxing dichloromethane, and its in situ trapping with (E)- and (Z)-1-methoxybut-2-en-3-yne to form (E)-1-methox