Zobrazeno 1 - 10
of 44
pro vyhledávání: '"D. N. Challacombe"'
Publikováno v:
Archives of Disease in Childhood. 77:206-209
An association was investigated between changing infant feeding practices and a declining incidence of childhood coeliac disease and transient gluten intolerance (TGI) in West Somerset, England during 1971-92. Dietary histories of 18 patients with co
Autor:
E E Wheeler, D N Challacombe
Publikováno v:
Gut. 40:57-60
BACKGROUND: Experimental evidence suggests that hormones may regulate small intestinal adaptation after surgical resection. AIMS: To characterise the effect of recombinant human growth hormone (GH), insulin-like growth factor-I (IGF-I) and insulin on
Publikováno v:
Gut. 32:1374-1377
Dietary supplementation with calcium may prevent the development of colorectal cancer. This mechanism may be related to fatty acid and bile salt chelation in the small bowel forming non-toxic calcium-soap compounds. Calcium may also act locally or sy
Publikováno v:
Gut. 32:1027-1030
Valuable information on intestinal adaptation can be gained by using the technique of organ culture to measure the crypt cell production rate. It is not known, however, whether the production rate in organ culture accurately represent that in vivo. C
Autor:
D. N. Challacombe, E. E. Wheeler, Robert J. Collier, Sharon M. Donovan, David R. Clemmons, J. I.D. Wilkinson
Publikováno v:
The Lancet. 344:815-817
Autor:
E E Wheeler, D N Challacombe
Publikováno v:
Gut. 32:991-993
The action of epidermal growth factor on the human duodenal mucosa has been studied by estimating the crypt cell production rate in cultured explants, using a stathmokinetic technique with crypt microdissection. The addition of epidermal growth facto
Autor:
D N Challacombe
Publikováno v:
Archives of Disease in Childhood. 73:3-4
Publikováno v:
Clinical Experimental Allergy. 13:263-269
Summary In a retrospective study the mothers of twenty-one children with well-defined cow's milk allergy and an equal number of matched controls were asked about their health and diet in pregnancy and the pattern of feeding of their children in infan
Autor:
E E Wheeler, D N Challacombe
Publikováno v:
Archives of Disease in Childhood. 59:523-527
Enterochromaffin cells in the duodenal mucosa were stained by using a monoclonal antibody against serotonin immunoreactive sites and an indirect immunoperoxidase technique. A semi-automatic image analysing system showed increased numbers of these cel
Autor:
D N Challacombe, E E Wheeler
Publikováno v:
Journal of Clinical Pathology. 38:1388-1393
Culture of peroral biopsy specimens from duodenal mucosa in vitro for 22 hours using a basic culture medium resulted in the formation of crypt cell nodules. The addition of collagen and serotonin to the culture medium increased the occurrence of the