Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D. Mrani"'
Akademický článek
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Autor:
Z. Tribak, A. Aouniti, R. Ghibate, D. Mrani, Belkheir Hammouti, Y. Kandri. Rodi, M.K. Skalli, O. Senhaji
Publikováno v:
International Journal of Engineering Research and Applications. :04-08
Autor:
D Mrani, Raymond Houssin, Lown Jw, Jean Louis Imbach, Pierre Colson, Claude Houssier, Michael J. Waring, Jean-Pierre Hénichart, Gilles Gosselin, Christian Bailly
Publikováno v:
Biochemistry. 31:8349-8362
We report the DNA binding properties of two hybrid molecules which result from the combination of the DNA sequence-specific minor groove ligand netropsin with the bithiazole moiety of the antitumor drug bleomycin. The drug-DNA interaction has been in
Autor:
R. Houssin, Jean Louis Imbach, Jan Balzarini, K. E. Rao, Christian Bailly, D Mrani, Gilles Gosselin, J.P. Hénichart, J. Zimmermann, Lown Jw, E. De Clercq
Publikováno v:
European Journal of Medicinal Chemistry. 27:331-344
A series of hybrid molecules have been synthesized which result from the combination of a DNA sequence-specific ligand (netropsin) coupled to a DNA-interactive structural component of bleomycins (bithiazole). The DNA binding affinities as well as the
Autor:
Jean Louis Imbach, Jan Balzarini, Gilles Gosselin, Christian Auclair, E. De Clercq, Claude Paoletti, D Mrani
Publikováno v:
European Journal of Medicinal Chemistry. 26:481-488
A series of bifunctional molecules have been synthesized which result from the combination of a DNA sequence-specific ligand (netropsin) coupled to an intercalator moiety (OPC). The binding constants to double-stranded polynucleotides as well as the
Autor:
Gilles Gosselin, Jacques Paoletti, Frédéric Subra, Jeanne Pager, Jean Louis Imbach, D Mrani, S. Carteau, Claude Paoletti, Christian Auclair
Publikováno v:
Biochemistry. 30:1642-1650
We have investigated some properties related to interaction with DNA and recognition of AT-rich sequences of netropsin-oxazolopyridocarbazole (Net-OPC) (Mrani et al., 1990), which is a hybrid groove-binder-intercalator. The hybrid molecule Net-OPC bi
Autor:
Bernard Rayner, Jean-Louis Aubagnac, Françoise Debart, D Mrani, Gilles Gosselin, Jean-Louis Imbach
Publikováno v:
Journal of Heterocyclic Chemistry. 28:145-151
The fast-atom bombardment (FAB) mass spectra of a series of netropsin derivatives and analogues were examined in positive-ion and when necessary negative-ion modes. Behaviour of these derivatives was related to that of oligopeptides. Some compounds p
Autor:
K E, Rao, G, Gosselin, D, Mrani, C, Périgaud, J L, Imbach, C, Bailly, J P, Hénichart, P, Colson, C, Houssier, J W, Lown
Publikováno v:
Anti-cancer drug design. 9(3)
The properties of certain hybrids 3 and 5 bearing a photoactivatable psoralen group attached to DNA sequence recognizing lexitropsin carriers have been examined. The hybrids bind to poly(dA-dT) with Kapp of 2.8 and 0.9 x 10(7) M-1, i.e. greater than
Autor:
Christian Auclair, Gilles Gosselin, Jean-Louis Imbach, Claude Paoletti, Frédéric Subra, D. Mrani
Publikováno v:
The Jerusalem Symposia on Quantum Chemistry and Biochemistry ISBN: 9789401056571
We have comparatively investigated some biochemical and pharmacological properties related to recognition of DNA AT-rich sequences of two hybrid groove binder-intercalators netropsin-oxazolopyridocarbazole (Net-OPC) and bis-pyrrolecarboxamide-oxazolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::754cdf217dd7dc73b638f344cb912052
https://doi.org/10.1007/978-94-011-3728-7_17
https://doi.org/10.1007/978-94-011-3728-7_17
Akademický článek
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