Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D. Margaret Hunt"'
Autor:
Richard L. Hall, Dallas Tower, Valery Z. Grdzelishvili, Sue A. Moyer, D. Margaret Hunt, Sherin Smallwood
Publikováno v:
Virology. 350:394-405
The vesicular stomatitis virus (VSV) L polymerase protein possesses two methyltransferase (MTase) activities, which catalyze the methylation of viral mRNA cap structures at the guanine-N7 and 2′-O-adenosine positions. To identify L sequences requir
Autor:
Richard L. Hall, Valery Z. Grdzelishvili, D. Margaret Hunt, Sherin Smallwood, Dallas Tower, Sue A. Moyer
Publikováno v:
Journal of Virology. 79:7327-7337
The vesicular stomatitis virus (VSV) RNA polymerase synthesizes viral mRNAs with 5′-cap structures methylated at the guanine- N 7 and 2′- O -adenosine positions (7mGpppA m ). Previously, our laboratory showed that a VSV host range ( hr ) and temp
Publikováno v:
Experimental Eye Research. 73:681-692
Growth in the presence of vitreous results in transformation of human RPE cells from an epithelioid to a fibroblast-like appearance and leads to an elevation of the expression of alpha(5) and alpha(2) integrins, while the level of alpha(3) integrin i
Publikováno v:
Journal of Cellular Physiology. 168:71-80
The existence of the blood-retinal barrier means that proteins that protect the retina from damage by reactive oxygen species must either be made locally or specifically transported across the barrier cells; however, such transepithelial transport do
Autor:
Joyce U Nair-Menon, Richard C. Hunt, D. Margaret Hunt, Sunil K. Parapuram, Binyue Chang, Kakarla V. Chalam, Ren A Hartung, Lei Li
Publikováno v:
Investigative ophthalmologyvisual science. 50(12)
Purpose In proliferative vitreoretinopathy retinal pigment epithelial (RPE) cells undergo epithelial-mesenchymal transformation (EMT). Vitreous and transforming growth factor-beta (TGFbeta) have been implicated in this EMT. The role of TGFbeta in the
Publikováno v:
Virology. 174:444-449
tsG16(l), a temperature-sensitive mutant of vesicular stomatitis virus, in vitro has at least three phenotypic differences from its parental wild-type (wt) virus due to mutation of the L gene. It was not known whether (i) the temperature-sensitivity
Publikováno v:
Investigative ophthalmologyvisual science. 48(4)
PURPOSE In proliferative vitreoretinopathy (PVR), retinal pigment epithelial (RPE) cells enter the vitreous and proliferate. They become fibroblast-like and participate in the formation of contractile membranes, which can lead to retinal detachment.
Autor:
Jehad Charo, Rolf Kiessling, Sunil K. Parapuram, Richard C. Hunt, Barbara Seliger, D. Margaret Hunt, Aniruddha Choudhury
Publikováno v:
International journal of cancer. 108(1)
Silencing of a specific mRNA using double stranded RNA oligonucleotides represents one of the newest technologies for suppressing a specific gene product. Small interfering RNA (siRNA) are 21 nucleotides long, double stranded RNA fragments that are i
Autor:
Gregory I, Liou, Suraporn, Matragoon, Sara, Samuel, M Ali, Behzadian, Nai-Tse, Tsai, Xiaolin, Gu, Penny, Roon, D Margaret, Hunt, Richard C, Hunt, Ruth B, Caldwell, Dennis M, Marcus
Publikováno v:
Molecular vision. 8
Hepatocyte growth factor (HGF) has been implicated in retinal pigment epithelial (RPE) cell proliferation and migration that occurs in proliferative retinal diseases such as proliferative vitreoretinopathy (PVR). The aim of this study is to investiga
Publikováno v:
Human pathology. 27(9)
Stromelysin-3 has been recently described in association with the stroma of different types of cancer including colorectal carcinomas. This article reports the detection of transcripts for stromelysin-3 (matrix metalloproteinase-11 [MMP-11]) in extra