Zobrazeno 1 - 3
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pro vyhledávání: '"D. M. Wynn"'
Publikováno v:
Clinical and Experimental Immunology. 164:330-336
Summary Anti-neutrophil cytoplasmic autoantibodies (ANCA) are a common feature of systemic vasculitides and have been classified as autoimmune conditions based, in part, on these autoantibodies. ANCA are subdivided further based on their primary targ
Publikováno v:
Clinical and Experimental Immunology. 162:262-270
Summary Many patients with Wegener's granulomatosis (WG) have anti-neutrophil cytoplasmic antibodies (c-ANCA). Aside from being a diagnostic marker, these autoantibodies may play roles in disease pathogenesis. Proteinase 3 (PR3) is the primary target
Publikováno v:
Cancer research. 53(23)
The expression of metalloproteinases, such as type IV collagenase/gelatinase, enables tumor cells to degrade type IV collagen present in the basement membrane and correlates with metastatic potential of several tumor types. We found that increased le