Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D. M. Umbach"'
Autor:
K. C. Gribben, A. B. Wyss, J. A. Poole, P. A. Farazi, C. Wichman, M. Richards-Barber, L. E. Beane Freeman, P. K. Henneberger, D. M. Umbach, S. J. London, T. D. LeVan
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/b0b89e4b443447f885bcd3c311097342
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background To evaluate statistical methods for genome-wide genetic analyses, one needs to be able to simulate realistic genotypes. We here describe a method, applicable to a broad range of association study designs, that can simulate autosom
Externí odkaz:
https://doaj.org/article/da48ff4903a8429bac2e54a2e61a6d5b
Autor:
K C, Gribben, A B, Wyss, J A, Poole, P A, Farazi, C, Wichman, M, Richards-Barber, L E, Beane Freeman, P K, Henneberger, D M, Umbach, S J, London, T D, LeVan
Publikováno v:
Respiratory Research. 23
Background The club cell secretory protein (CC16) has anti-inflammatory and antioxidant effects and is a potential early biomarker of lung damage. The CC16 single nucleotide polymorphism (SNP) rs3741240 risk allele (A) has been inconsistently linked
Autor:
R A, Popat, S K, Van Den Eeden, C M, Tanner, F, Kamel, D M, Umbach, K, Marder, R, Mayeux, B, Ritz, G W, Ross, H, Petrovitch, B, Topol, V, McGuire, S, Costello, A D, Manthripragada, A, Southwick, R M, Myers, L M, Nelson
Publikováno v:
European journal of neurology. 18(5)
In 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine animal models of Parkinson's disease (PD), caffeine protects neurons by blocking the adenosine receptor A2A (ADORA2A). Caffeine is primarily metabolized by cytochrome P450 1A2 (CYP1A2). Our objective wa
Publikováno v:
Journal of Economic Entomology. 83:1541-1548
Mortality response to a 30-min exposure to low temperature was studied for all stages of the potato leafhopper, Empoasca fabae (Harris). The relationship between mortality and temperature fit a linear logistic regression model for each stage from egg
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)
The incidence of hepatocellular carcinomas (HCC) varies widely worldwide, with some of the highest incidence rates found in China. Chronic infection with the hepatitis B virus (HBV) and exposure to aflatoxins in foodstuffs are the main risk factors.
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(2)
Bladder cancer is the sixth most common cancer in the United States. The main identified risk factor is cigarette smoking, which is estimated to contribute to up to 50% of new cases in men and 20% in women. Besides containing other carcinogens, cigar
Publikováno v:
International journal of cancer. 87(4)
In humans, aromatic and heterocyclic amine carcinogens may be acetylated by the expression products of either of the N-acetyltransferase genes, NAT1 or NAT2. This conjugation reaction can result in either activation or detoxication of these carcinoge
Publikováno v:
Molecular carcinogenesis. 27(1)
Prostate cancer is a common disease, yet determinants of prostate cancer risk remain largely unidentified. Low circulating levels of 1, 25-dihydroxy vitamin D (1,25-D) have been implicated as a risk factor for prostate cancer. In addition, 1,25-D exh
Publikováno v:
Genetic epidemiology. 17
A two-stage approach was used to analyze Problem 2 simulated data from Genetic Analysis Workshop 11. In the first stage, we tested for linkage with the Haseman-Elston test in SIBPAL. Markers that were significant in the first stage were followed up w