Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D. M. Stemerick"'
Autor:
Jennifer A. Dumont, Albert Sjoerdsma, Edwards Michael L, Alan J. Bitonti, Peter P. McCann, Philippe Bey, D. M. Stemerick
Publikováno v:
ChemInform. 22
A series of novel tetraamines of the general formula RNH(CH2)xNH(CH2)yNH(CH2)xNHR was synthesized and examined for activity against growth of Plasmodium falciparum in vitro. Within the series, dibenzyl analogues (R = benzyl) were found to be the most
Autor:
Jennifer A. Dumont, Alan J. Bitonti, Edwards Michael L, Peter P. McCann, D. M. Stemerick, Philippe Bey, Albert Sjoerdsma
Publikováno v:
Journal of medicinal chemistry. 34(2)
A series of novel tetraamines of the general formula RNH(CH2)xNH(CH2)yNH(CH2)xNHR was synthesized and examined for activity against growth of Plasmodium falciparum in vitro. Within the series, dibenzyl analogues (R = benzyl) were found to be the most
Publikováno v:
The Journal of biological chemistry. 265(1)
N,N'-Bis(benzyl)polyamine analogs were found to be substrates for highly purified polyamine oxidase. Metabolism of these analogs was apparently dependent on molecular O2 and resulted in the formation of benzaldehyde, H2O2, and a polyamine analog with
Publikováno v:
Journal of Medicinal Chemistry. 26:431-436
Publikováno v:
Chemischer Informationsdienst. 14