Zobrazeno 1 - 3
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pro vyhledávání: '"D. M. Spitkovsky"'
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 42(6)
The most important stage in the making of mutations is a reparation of different DNA damage, including the more deleterious double-strand DNA breaks (DSB). The first stage of adaptive response--fundamental antimutagenic cell reaction, purposeful to r
Autor:
D M, Spitkovsky
Publikováno v:
Biochemistry. Biokhimiia. 62(11)
Dynamics of telomere sequences are considered in normal and immortalized cells. Immortalized cells are suggested to be derived mainly from a special subpopulation of ontogenetic reserve cells. Their epigenetic program consists of autoregeneration dur
Publikováno v:
Human Genetics. 28:183-189
In the chromatin of patients with Down's syndrome, changes are shown to occur in a short-term lymphocyte culture of the human peripheral blood. Some of them are induced by the patient's blood serum and are reversible when this is replaced by normal s