Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D. M. Shih"'
Autor:
C E, Furlong, W F, Li, V H, Brophy, G P, Jarvik, R J, Richter, D M, Shih, A J, Lusis, L G, Costa
Publikováno v:
Neurotoxicology. 21(4)
It has been assumed since its discovery that serum paraoxonase (PON1) plays a major role in the detoxication of specific organophosphorus compounds. It was also assumed that individuals with low PON1 activity would be more susceptible to paraoxon/par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::234f7bdda0ec0b34ce534b0fc2bebfd5
https://pubmed.ncbi.nlm.nih.gov/11022865
https://pubmed.ncbi.nlm.nih.gov/11022865
Publikováno v:
Neurotoxicology. 21(1-2)
Susceptibility to organophosphorus (OP) insecticides and nerve agents is strongly influenced by genetic and developmental factors. A number of organophosphorothioate insecticides are detoxified in part via a two-step pathway involving bioactivation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22da5b0c5d6efdc2c4d7046657d99d4d
https://pubmed.ncbi.nlm.nih.gov/10794389
https://pubmed.ncbi.nlm.nih.gov/10794389
Publikováno v:
Neurotoxicology. 19(4-5)
Several organophosphorus insecticides and nerve agents are detoxified through the cytochrome P450/paraoxonase (PON1) pathway. PON1 is an HDL-associated enzyme encoded as a 355 amino acid protein in humans. The PON1 Arg192 isoform hydrolyzes paraoxon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1ca3fd0447004b8abb2c2ac259cf1fd
https://pubmed.ncbi.nlm.nih.gov/9745924
https://pubmed.ncbi.nlm.nih.gov/9745924
Publikováno v:
The Journal of biological chemistry. 268(5)
When introduced as part of DNA constructions containing the human beta-globin locus control region (LCR), the human embryonic beta-globin gene, epsilon, is expressed in primitive but not definitive erythroid cells of recipient transgenic mice. In con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::feb4f24e59265635e27ba408969a660e
https://pubmed.ncbi.nlm.nih.gov/8428985
https://pubmed.ncbi.nlm.nih.gov/8428985
Publikováno v:
Carcinogenesis. 29:2432-2432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b64e569cf7c366b878d67441282fff
https://doi.org/10.1093/carcin/bgn254
https://doi.org/10.1093/carcin/bgn254