Zobrazeno 1 - 10
of 46
pro vyhledávání: '"D. M. Shasby"'
Autor:
Anant Kamath, Ken Blackwell, Alan B. Moy, D. M. Shasby, Charles R. Keese, Michael C. Winter, Ivar Giaever, Gina M. Reyes
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 278:L888-L898
To determine how histamine regulates endothelial barrier function through an integrative cytoskeletal network, we mathematically modeled the resistance across an endothelial cell-covered electrode as a function of cell-cell, cell-matrix, and transcel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be4d17b32f9db00800b3bdc2634fa4f
https://doi.org/10.1152/ajplung.2000.278.5.l888
https://doi.org/10.1152/ajplung.2000.278.5.l888
Autor:
S. S. Shasby, Anant Kamath, D. M. Shasby, Troy Stevens, Alan B. Moy, J. M. Kamath, Dana R. Ries
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 272:L311-L319
Histamine and thrombin increase myosin light-chain kinase-mediated phosphorylation of myosin light chain (MLC) in human umbilical vein endothelial cells (HUVEC). The increase in MLC phosphorylation caused by thrombin persists longer (330 min) than th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c872961947298a66b6519ecba94fdc
https://doi.org/10.1152/ajplung.1997.272.2.l311
https://doi.org/10.1152/ajplung.1997.272.2.l311
Autor:
D M Shasby, J Van Engelenhoven, Ivar Giaever, Charles R. Keese, S. S. Shasby, J. M. Kamath, James E. Bodmer, Alan B. Moy
Publikováno v:
Journal of Clinical Investigation. 97:1020-1027
We examined the contribution of actin-myosin contraction to the modulation of human umbilical vein endothelial cell focal adhesion caused by histamine and thrombin. Focal adhesion was measured as the electrical resistance across a cultured monolayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df211eecd6b32f1447089552abfec0a
https://doi.org/10.1172/jci118493
https://doi.org/10.1172/jci118493
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 269:L144-L150
It has been hypothesized that modulation of epithelial paracellular permeability may be mediated by initiation of contraction of a band of actin and myosin located at the tight junction. Phosphorylation of myosin light chain (MLC) is an important det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a58531decacfb18fe1bc21e86432608
https://doi.org/10.1152/ajplung.1995.269.2.l144
https://doi.org/10.1152/ajplung.1995.269.2.l144
Publikováno v:
Journal of Clinical Investigation. 92:1198-1206
Histamine causes adjacent endothelial cells to retract from each another. We examined phosphorylation of the 20-kD myosin light chain (MLC20) in human umbilical vein endothelial cells (HUVECs) exposed to histamine to determine if we could find eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3466d59136a71d673288181c26e65dc2
https://doi.org/10.1172/jci116690
https://doi.org/10.1172/jci116690
Autor:
Michael L. McCormick, Charles D. Cox, T.L. Roeder, George T. Rasmussen, D M Shasby, Bradley E. Britigan
Publikováno v:
Journal of Clinical Investigation. 90:2187-2196
Pyocyanin, a secretory product of Pseudomonas aeruginosa, has the capacity to undergo redox cycling under aerobic conditions with resulting generation of superoxide and hydrogen peroxide. By using spin trapping techniques in conjunction with electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94613a588d3340c7f9585ef99f78edb3
https://doi.org/10.1172/jci116104
https://doi.org/10.1172/jci116104
Publikováno v:
Blood. 79:699-707
Spin trapping, a sensitive and specific means of detecting free radicals, is optimally performed on cell suspensions. This makes it unsuitable for the study of adherent endothelial cell monolayers because disrupting the monolayer to induce a cell sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2dfcbafddef47288b00d5435758b47
https://doi.org/10.1182/blood.v79.3.699.699
https://doi.org/10.1182/blood.v79.3.699.699
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 4:470-477
Oxidants reversibly increase the paracellular permeability of Madin Darby canine kidney (MDCK) epithelial cell monolayers, and the decrease in resistance occurs within 10 to 15 min of initiating oxidant exposure. Oxidants also initiate hydrolysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be866ca184d656f3941dfab93b27db54
https://doi.org/10.1165/ajrcmb/4.5.470
https://doi.org/10.1165/ajrcmb/4.5.470
Publikováno v:
Blood. 76:2578-2582
Oxidants can reversibly increase the permeability of endothelium to ions and macromolecules. Oxidants also deplete ATP in cultured endothelial cells. We asked if oxidant-mediated ATP depletion, alone, accounted for the effects of oxidants on endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac2effab97cfbddba49154ec7506fe3
https://doi.org/10.1182/blood.v76.12.2578.bloodjournal76122578
https://doi.org/10.1182/blood.v76.12.2578.bloodjournal76122578
Publikováno v:
Infection and Immunity. 63:4921-4923
Pseudomonas aeruginosa pneumonia causes a vasculitis of small pulmonary arteries. While the fully developed lesion demonstrates vessel wall necrosis, the early lesion is remarkable for preservation of viable endothelium despite vessel wall invasion b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd71e06fb248e8bd0d017eb859f7a566
https://doi.org/10.1128/iai.63.12.4921-4923.1995
https://doi.org/10.1128/iai.63.12.4921-4923.1995