Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D. M. Sabatini"'
Autor:
S. R. Floyd, M. E. Pacold, S. M. Clarke, E. Blake, A. Fydrych, R. Ho, M. J. Lee, D. E. Root, A. E. Carpenter, D. M. Sabatini, C. A. French, J. E. Bradner, C. C. Chen, M. B. Yaffe, E. Le Rhun, F. Massin, A. Lefevre, J. Bonneterre, M. d. C. Bittencourt, G. Faure, R. Hiramatsu, S. Kawabata, Y. Yamada, S.-I. Miyatake, T. Kuroiwa, S. Li, A. P. Chou, W. Chen, R. Chen, Y. Deng, H. S. Phillips, K. F. Faull, T. Cloughesy, L. M. Liau, A. Lai, K. Mori, R. Ishikura, Y. Tomogane, S. Izumoto, N. Arita, J. Piao, G. Auyeung, E. Policarpio, V. Tabar, T. P. C. Yeung, L. Morrison, L. Hoffman, T.-Y. Lee, G. Bauman, S. Yartsev, S. Ryu, A. Kolozsvary, M. Lapanowski, K. Jenrow, S. Brown, J. H. Kim, R. J. Brown, J. Love, D. Warburton, W. McBride, S. Bluml, X. Ren, B. Vanderwaal, J. Jaboin, A. L. Baldock, S. Anh, R. Rockne, M. Neal, K. Clark-Swanson, G. Sterin, A. D. Trister, H. Malone, V. Ebiana, A. M. Sonabend, M. Mrugala, J. K. Rockhill, D. L. Silbergeld, G. M. McKhann, J. N. Bruce, R. Rostomily, P. Canoll, K. R. Swanson, A. Hawkins-Daarud, A. Baldock, C. Bridge, D. Corwin, M. M. Mrugala, K. Yagle, D. Born, P. Swanson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4315b493a8cfb630ce2102923945ac
https://europepmc.org/articles/PMC3488791/
https://europepmc.org/articles/PMC3488791/
Autor:
M. Laplante, D. M. Sabatini
Publikováno v:
Cold Spring Harbor perspectives in biology. 4(2)
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that integrates environmental cues (e.g., growth factors and energy status) to control cell growth and proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38de7c4863c4f32f39caea7d5818fd5
https://pubmed.ncbi.nlm.nih.gov/22129599
https://pubmed.ncbi.nlm.nih.gov/22129599
Autor:
D H, Kim, D M, Sabatini
Publikováno v:
Current topics in microbiology and immunology. 279
mTOR/RAFT1/FRAP is the target of the FKBP12-rapamycin complex as well as a central component of a nutrient- and hormone-sensitive pathway that controls cellular growth. Recent work reveals that mTOR interacts with a novel evolutionarily conserved pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91ab2d2c3a139d80127da5d4cb3a5882
https://pubmed.ncbi.nlm.nih.gov/14560962
https://pubmed.ncbi.nlm.nih.gov/14560962
Autor:
L D, Walensky, T M, Dawson, J P, Steiner, D M, Sabatini, J D, Suarez, G R, Klinefelter, S H, Snyder
Publikováno v:
Molecular medicine (Cambridge, Mass.). 4(8)
BACKGROUND: The 12 kD FK506 binding protein FKBP12 is a cytosolic receptor for the immunosuppressant drugs FK506 and rapamycin. In addition to its critical role in drug-induced T-cell immunosuppression, FKBP12 associates physiologically with ryanodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76ae0c2941ad42b32ae69636ec454c74
https://pubmed.ncbi.nlm.nih.gov/9742506
https://pubmed.ncbi.nlm.nih.gov/9742506
Autor:
S H, Snyder, D M, Sabatini
Publikováno v:
Nature medicine. 1(1)
The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cells, especially in the nervous and immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7dce71bb87fa5b1ed5923ffa88e01287
https://pubmed.ncbi.nlm.nih.gov/7584950
https://pubmed.ncbi.nlm.nih.gov/7584950