Zobrazeno 1 - 10 of 11 pro vyhledávání: '"D. M. SCHIAVO"'
2
Tapetal changes in beagle dogs following oral administration of CGS 14796C, a potential aromatase inhibitor*1
Autor: Vincent M. Traina, R. Spaet, J. D. Green, I. Zaidi, D. M. Schiavo
Publikováno v: Fundamental and Applied Toxicology. 10:329-334
CGS 14796C, cis -1-[(4-[(1-imidazolyl)methyl]-cyclohexyl)methyl)imidazole succinate, has been evaluated as a potential aromatase inhibitor. As part of the safety evaluation program, a 3-month oral toxicity study was performed in which beagle dogs wer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddfc48374ab9b9975a8ca62ba10547a6
https://doi.org/10.1016/0272-0590(88)90318-1
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4
Multifocal retinal dysplasia in the Syrian hamster LAK:LVG (SYR)
Autor: D M, Schiavo
Publikováno v: Journal of environmental pathology and toxicology. 3(5-6)
Multifocal retinal dysplasia was diagnosed clinically in twenty-four of twelve hundred (2.0% incidence) LAK:LVG (SYR) Syrian Hamsters. The affected hamsters were part of twelve hundred animals to be used in oncogenic studies. Ther dysplastic retina w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ebb02c9dddef32c2ceb399843c351521
https://pubmed.ncbi.nlm.nih.gov/7441100
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5
Tapetal changes in beagle dogs. I. Ocular changes after oral administration of a beta-adrenergic blocking agent--SCH 19927
Autor: D M, Schiavo, D P, Sinha, H E, Black, L, Arthaud, T, Massa, B F, Murphy, R J, Szot, E, Schwartz
Publikováno v: Toxicology and applied pharmacology. 72(2)
SCH 19927 [R,R)-(-)-2-Hydroxy-5-[1-hydroxy-2-[(1-methyl -3-phenylpropyl)amino]ethyl]benzamide hydrochloride) is a beta-adrenergic blocking agent which has vasodilating properties. In a subchronic oral toxicity study in beagle dogs, SCH 19927 was give
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f35d5353525451331da22108d5f4f4b0
https://pubmed.ncbi.nlm.nih.gov/6695371
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7
Tapetal changes in beagle dogs following oral administration of CGS 14796C, a potential aromatase inhibitor
Autor: D M, Schiavo, J D, Green, V M, Traina, R, Spaet, I, Zaidi
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 10(2)
CGS 14796C, cis-1-[(4-[(1-imidazolyl)methyl]-cyclohexyl)methyl)imidazole succinate, has been evaluated as a potential aromatase inhibitor. As part of the safety evaluation program, a 3-month oral toxicity study was performed in which beagle dogs were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::59f8fa99ef179340e805df5eb6b77e37
https://pubmed.ncbi.nlm.nih.gov/3356320
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8
A rapid testing procedure to determine low levels of ocular irritation
Autor: S, Gupta, D M, Schiavo
Publikováno v: Laboratory animal science. 26(3)
A new and rapid method for testing low levels of ocular irritation using a balanced incomplete block design, a new grading system, and statistical analysis of the results, has been developed. Two drops (0.1 ml) of 1 of 5 ophthalmic solutions were ins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::327e69646d15da0ab9d2c1dd9f5ed4fa
https://pubmed.ncbi.nlm.nih.gov/940308
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