Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D. M. Rosen"'
Autor:
O. C. Rogers, D. M. Rosen, L. Antony, H. M. Harper, D. Das, X. Yang, I. Minn, R. C. Mease, M. G. Pomper, S. R. Denmeade
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Prostate cancer cells are characterized by a remarkably low proliferative rate and the production of high levels of prostate-specific proteases. Protein-based toxins are attractive candidates for prostate cancer therapy because they kill cel
Externí odkaz:
https://doaj.org/article/9ccc999bbc6e4ef58648953c074fc96c
Autor:
Ronnie C. Mease, Martin G. Pomper, Samuel R. Denmeade, D. M. Rosen, Lizamma Antony, O. C. Rogers, Xiaoping Yang, H. M. Harper, Deepankar Das, Il Minn
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Prostate cancer cells are characterized by a remarkably low proliferative rate and the production of high levels of prostate-specific proteases. Protein-based toxins are attractive candidates for prostate cancer therapy because they kill cells via pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d8ee9222b9c7ff58539f8aa80fe63c
https://pubmed.ncbi.nlm.nih.gov/34290365
https://pubmed.ncbi.nlm.nih.gov/34290365
Autor:
D. M. Rosen, Benjamin Se, Julie L. Eiseman, Dorothy L. Sentz, P. S. Callery, Merrill J. Egorin
Publikováno v:
Cancer Chemotherapy and Pharmacology. 41:9-14
Objectives: To characterize the enzymes responsible for and metabolites produced from the metabolism of halomon, a halogenated monoterpene that is isolated from the red algae Portieria hornemanii and has in vitro activity in the NCI screen against br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73428add0aa9698321fee1b22fdaf53
https://doi.org/10.1007/s002800050701
https://doi.org/10.1007/s002800050701
Autor:
Susan L. Dalrymple, Craig A. Dionne, Jesper V. Møller, Angelo M. DeMarzo, Samuel R. Denmeade, Bora Gurel, D. M. Rosen, W. N. Brennen, Poul Nissen, Ingrid Dach, George Wilding, Claus Olesen, Søren Brøgger Christensen, John T. Isaacs, Annastasiah Mhaka, Michael A. Carducci
Publikováno v:
Science Translational Medicine. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7efeb6206fec77e5c5a945959a6132b
https://doi.org/10.1126/scitranslmed.3004546
https://doi.org/10.1126/scitranslmed.3004546
Autor:
S. R. Denmeade, A. M. Mhaka, D. M. Rosen, W. N. Brennen, S. Dalrymple, I. Dach, C. Olesen, B. Gurel, A. M. DeMarzo, G. Wilding, M. A. Carducci, C. A. Dionne, J. V. Moller, P. Nissen, S. B. Christensen, J. T. Isaacs
Publikováno v:
Science Translational Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=erc_________::b94212f8084c5e77d84ebcb7df14532c
Autor:
David J. Weber, Samuel R. Denmeade, D M Rosen, Morassa Mohseni, Kurtis E. Bachman, M B Weiss, Michele Vitolo, Ben Ho Park
Publikováno v:
Oncogene. 29(33)
The TP53 tumor suppressor gene is the most commonly mutated gene in human cancers. To evaluate the biological and clinical relevance of p53 loss, human somatic cell gene targeting was used to delete the TP53 gene in the non-tumorigenic epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f34b03a1060a52e7b7d2c5b8a19ee0
https://pubmed.ncbi.nlm.nih.gov/20562907
https://pubmed.ncbi.nlm.nih.gov/20562907
Akademický článek
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Autor:
David I. Rosenthal, Eugene P. Frenkel, M. J. Egorin, D. M. Rosen, Ara A. Chalian, D. A. Yardley, Linda Miller, Jason H. Lee, R. J. Sinard, Gregory S. Weinstein, D. P. Carbone, Mitchell Machtay, R.S. Weber
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 19(5)
PURPOSE: Paclitaxel is one of the most active agents for squamous cell carcinoma of the head and neck (SCCHN) and an in vitro radiosensitizer. The dose-response relationship for paclitaxel may depend more on exposure duration than on peak concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fd1faeb5cefce72d2659aedf5627a1
https://pubmed.ncbi.nlm.nih.gov/11230480
https://pubmed.ncbi.nlm.nih.gov/11230480
Autor:
P M, Fracasso, P, Westervelt, C L, Fears, D M, Rosen, E G, Zuhowski, L A, Cazenave, M, Litchman, M J, Egorin, P, Westerveldt, C A, Fears
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 18(5)
PURPOSE: To determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of paclitaxel when given with PSC 833 (valspodar) to patients with refractory solid tumors. PATIENTS AND METHODS: Patients were initially treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41466b6a89393a830dda8ce1cd55c8ae
https://pubmed.ncbi.nlm.nih.gov/10694566
https://pubmed.ncbi.nlm.nih.gov/10694566
Autor:
Julie L. Eiseman, Suhlan Wu, Dorothy L. Sentz, M. Wollman, D. M. Rosen, T. S. Ramsland, B. A. Conley
Publikováno v:
Cancer chemotherapy and pharmacology. 43(3)
Purpose: The efficacy of 13-cis-retinoic acid (13-CRA) given as a single agent or in combination with tamoxifen (TAM) was determined in athymic nude mice bearing advanced s.c. MCF-7 human breast cancers. Methods: 13-CRA alone was given by gavage at d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852a6a70ed78094b3385fdd4cd68798c
https://pubmed.ncbi.nlm.nih.gov/9923548
https://pubmed.ncbi.nlm.nih.gov/9923548