Zobrazeno 1 - 6
of 6
pro vyhledávání: '"D. M. Rodman"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 266:L469-L475
Changes in oxygen tension in the perinatal period contribute to high pulmonary vascular tone in the fetus and the decline in resistance that occurs at birth. Distal pulmonary artery smooth muscle cells (PASMC) isolated from late-gestation ovine fetus
Publikováno v:
Respiratory Research
Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of
Publikováno v:
The American journal of physiology. 265(1 Pt 1)
We studied the effect of acute hypoxia on the cytosolic calcium concentration ([Ca2+]i) of fetal vascular smooth muscle cells (SMC) from late gestation fetal lambs. We tested the following hypotheses: 1) fetal pulmonary artery (PA) SMC sense hypoxia;
Publikováno v:
The American journal of physiology. 263(5 Pt 2)
To study the potential role of ATP-sensitive K+ (K+ATP) channels in fetal pulmonary vasoregulation, we studied the effect of a K+ATP channel agonist, lemakalim, and antagonist, glibenclamide, on the fetal pulmonary circulation in nine chronically ins
Publikováno v:
Chest. 93:88S-93
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 248(3)
This study was undertaken to test if isolated rat pulmonary artery (PA) rings contract in response to hypoxia, if the response behaves similarly to previously described physiologic and pharmacologic features of hypoxic pulmonary vasoconstriction (HPV