Zobrazeno 1 - 10
of 16
pro vyhledávání: '"D. M. Mitrovic"'
Publikováno v:
Journal of Chemotherapy. 7:543-548
Tiazofurine is a selective inhibitor of the enzyme inosine monophosphate dehydrogenase, and exhibits potent antitumor activity. Considering the potential side effects on the heart, [3H] tiazofurine uptake into the cardiomyocytes, as well as the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fdcf3d4cf407fb06169a3956bbbe61
https://doi.org/10.1179/joc.1995.7.6.543
https://doi.org/10.1179/joc.1995.7.6.543
Autor:
Christopher C.W. Hughes, John Greenwood, David J. Begley, D. M. Mitrovic, Linda K. Squires, Patricia A. Revest, Berislav V. Zlokovic
Publikováno v:
Journal of Neurochemistry. 55:1222-1230
Uptake of the immunosuppressive lipophilic peptide cyclosporin A has been measured by a number of techniques. The brain uptake index (BUI) technique in the rat yields only a small BUI value that is not significantly different from that of sucrose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca7b1f19fe6a31615c50538254bad3a
https://doi.org/10.1111/j.1471-4159.1990.tb03128.x
https://doi.org/10.1111/j.1471-4159.1990.tb03128.x
Publikováno v:
Scopus-Elsevier
We present a review about the relationship between ryanodine receptors and voltage-gated calcium channels in myocardium, and also how both of them are related to protein kinase A. Ryanodine receptors, which have three subtypes (RyR1-3), are located o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72afccc39ec8f4c5c3a081a92e987c9a
https://pubmed.ncbi.nlm.nih.gov/17465689
https://pubmed.ncbi.nlm.nih.gov/17465689
Autor:
Z B, Redzic, I D, Markovic, S S, Jovanovic, J M, Gasic, D M, Mitrovic, B V, Zlokovics, L M, Rakic
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 18(6)
Tiazofurin is a nucleoside analog with potent antitumor activity. The objective of this study was to define the kinetic parameters of tiazofurin transport from blood into the guinea pig brain. The second aim was to define kinetic parameters of tiazof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d603d96877a9e45a0c69341d71a2494d
https://pubmed.ncbi.nlm.nih.gov/8892271
https://pubmed.ncbi.nlm.nih.gov/8892271
Publikováno v:
Biology and Physiology of the Blood-Brain Barrier ISBN: 9781475794915
Transport of 3H L-alanine through the blood-brain barrier (BBB) was studied using brain vascular perfusion method in guinea pig. Our results indicate that L-alanine passes across the luminal side of the BBB. Unidirectional transport constant Kin rang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aaf91e5c5a71932408756e79981ab88
https://doi.org/10.1007/978-1-4757-9489-2_7
https://doi.org/10.1007/978-1-4757-9489-2_7
Publikováno v:
Biology and Physiology of the Blood-Brain Barrier ISBN: 9781475794915
Transport of tiazofurin (2-β-D-ribofuranosyl thiazole-4-carboxamide) across the blood-brain barrier (BBB) was studied using brain vascular perfusion method in the guinea pig. The obtained results demonstrate that brain clearance of 3H tiazofurin sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6e3d66b9b16b6f58732e9f4784a9042
https://doi.org/10.1007/978-1-4757-9489-2_26
https://doi.org/10.1007/978-1-4757-9489-2_26
Publikováno v:
Biology and Physiology of the Blood-Brain Barrier ISBN: 9781475794915
Distribution of radio labelled small neutral amino acids between endothelial cells and brain parenchyma after transport across the luminal side of the blood-brain barrier was studied in guinea pig. After in situ brain vascular perfusion, the capillar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6ff97bb483877c8e4fb23c62ebb7d7
https://doi.org/10.1007/978-1-4757-9489-2_8
https://doi.org/10.1007/978-1-4757-9489-2_8
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 17(6)
The aim of this study was to investigate the transport of tiazofurin (2-beta-D-ribofuranosyl thiazole-4-carboxamide) across the blood-brain barrier (BBB) using brain vascular perfusion and capillary depletion method in the guinea pig. Values for volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2206907b9b13427ae4d2ea82fbfd19e2
https://pubmed.ncbi.nlm.nih.gov/8642902
https://pubmed.ncbi.nlm.nih.gov/8642902
Autor:
D. M. Mitrovic, Z. Redžić, J. B. Mackic, Lj. Rakić, Milo N. Lipovac, Hugh Davson, R. Veskov, Malcolm B. Segal, Berislav V. Zlokovic
Publikováno v:
Barriers and Fluids of the Eye and Brain ISBN: 9781349123087
We applied the brain vascular perfusion method to determine the kinetics of entry to inert polar molecular D-[3H]-mannitol into the parietal cortex, hippocampus and caudate nucleus in guinea-pigs with sensorimotor (SM) and occipital (Oc) cortical les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ed3b0f72eacd034c936676a91c82d2
https://doi.org/10.1007/978-1-349-12306-3_14
https://doi.org/10.1007/978-1-349-12306-3_14
Autor:
David J. Begley, Milo N. Lipovac, D. M. Mitrovic, Ratko M. Jankov, Hugh Davson, Berislav V. Zlokovic, Veselinka T. Susic
Publikováno v:
Peptides. 10:249-254
Cellular uptake of [125I] labelled DSIP at the luminal interface of the blood-brain barrier (BBB) was studied in the ipsilateral perfused in situ guinea pig forebrain. Regional unidirectional transfer constants (Kin) calculated from the multiple-time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774946dd20d76277975fab60218f03d7
https://doi.org/10.1016/0196-9781(89)90026-0
https://doi.org/10.1016/0196-9781(89)90026-0