Zobrazeno 1 - 2
of 2
pro vyhledávání: '"D. M. Makarova"'
Autor:
Elena L. Chernolovskaya, Marina A. Zenkova, D. M. Makarova, Ivan V. Chernikov, Elena V. Shmendel, N. G. Morozova, S. A. Bakhareva, M. A. Maslov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 46:1250-1260
New uncharged gemini-amphiphiles have been synthesized. A series of cationic liposomes based on the polycationic amphiphile 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride (2X3), 1,2-dioleoyl-sn-glycero-3
Publikováno v:
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES. :165-167
Micelle-forming symmetric lipophilic polyamines were obtained. Minimal CMC values were defined for norspermine- based derivatives. Cytotoxicity test of symmetric lipophilic polyamines showed a increase of IC50 in comparison of unsymmetrical analogs.