Zobrazeno 1 - 8 of 8 pro vyhledávání: '"D. M. MARYNIAK"'
1
Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-CAM. Direct observation of an intermolecular isotope effect for substrate C-H activation
Autor: S, Kadkhodayan, E D, Coulter, D M, Maryniak, T A, Bryson, J H, Dawson
Publikováno v: The Journal of biological chemistry. 270(47)
The hydroxylation of (1R)-camphor by cytochrome P450-CAM involves almost complete coupling of electron to oxygen transfer. Modifications at C-5 of camphor, the normal site of hydroxylation by P450-CAM, lead to as much as 98% uncoupling of electron an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c50cb726b6f79b9e69a989716ff7d78a
https://pubmed.ncbi.nlm.nih.gov/7499289
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3
Studies on antifungal agents. In vitro activity of novel cis-5-alkoxy (or acyloxy)alkyl-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidine derivatives
Autor: D M, Maryniak, G B, Mullen, S D, Allen, J T, Mitchell, C R, Kinsolving, V, St Georgiev
Publikováno v: Arzneimittel-Forschung. 40(1)
The synthesis and in vitro antifungal activity of a novel series of cis-5-alkoxy(or acyloxy)alkyl-3-phenyl-3-(1H-imidazol-1-ylmethyl)- 2-methylisoxazolidine derivatives (6a-n) are described. The 5-[(4-chlorobenzyloxy)methyl] analogue 6h and the two 5
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efe184e4c891fc3fbb86f9fcd25885c7
https://pubmed.ncbi.nlm.nih.gov/2340006
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4
Adamantylmethyl analogues of chloramphenicol
Autor: L. A. Radov, Laura A Trusso, Vassil St. Georgiev, G. B. Mullen, D. M. Maryniak
Publikováno v: European Journal of Medicinal Chemistry. 24:271-276
The synthesis and biological activity of novel adamantylmethyl analogues of chloramphenicol are described. Substituting the polar para -nitro group on the phenyl ring with a non-polar lipophilic adamantylmethyl moiety resulted in a diminished antimic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf998c9075dbd859a4e4fae0f00b0222
https://doi.org/10.1016/0223-5234(89)90009-3
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6
Antifungal activity of novel 5-carbonyl derivatives of 3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines
Autor: W. E. Jones, S. D. Allen, Thomas R. DeCory, J. T. Mitchell, Vassil St. Georgiev, D. M. Maryniak, Grace A. Bennett, George B. Mullen
Publikováno v: Archiv der Pharmazie. 322(9)
The synthesis and antifungal activity of a series of novel 5-carbonyl derivatives of 3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines (4) are discussed. The preparation of the title compounds involved a 1,3-dipolar cycloaddition reaction of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceb89a3e7bcb2ef4671273a96f821fb
https://pubmed.ncbi.nlm.nih.gov/2610586
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7
ChemInform Abstract: In vitro Activity of Novel 5-Carbonyl Derivatives of 3-Phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines
Autor: S. D. Allen, W. E. Jones, Thomas R. DeCory, J. T. Mitchell, George B. Mullen, Vassil St. Georgiev, D. M. Maryniak, Grace A. Bennett
Publikováno v: ChemInform. 20
The synthesis and antifungal activity of a series of novel 5-carbonyl derivatives of 3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines (4) are discussed. The preparation of the title compounds involved a 1,3-dipolar cycloaddition reaction of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f79f96767f151bd0cd0d68967ed1b0a
https://doi.org/10.1002/chin.198926341
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