Zobrazeno 1 - 10 of 41 pro vyhledávání: '"D. M. Irodov"'
2
Obtaining of the recombinant Rhil7-Cbd fusion protein
Autor: M. O. Usenko, M. V. Koval’chuk, D. M. Irodov, O. B. Gorbatiuk, O. V. Okunev, V. A. Kordium
Publikováno v: Faktori eksperimental'noi evolucii organizmiv. 26:282-286
Aim. The purpose was to obtain the recombinant fusion protein based on the human interleukin-7 (rhIL7) and cellulose binding domain (CBD). Methods. The DNA sequences encoding rhIL-7 and CBD were subcloned into the pET24a(+). Vector containing the 6Hi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e79d173a2317b75a305e51f179439dee
https://doi.org/10.7124/feeo.v26.1280
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3
Obtaining of the recombinant rhIL7-BAPmut fusion protein and its functional characterization
Autor: O. V. Okunev, D. M. Irodov, V. A. Kordium, K. I. Bentsionova, M. O. Usenko, O. B. Gorbatiuk
Publikováno v: Faktori eksperimental'noi evolucii organizmiv. 25:321-326
Aim. The purpose was to obtain a functionally active form of the recombinant fusion protein based on the human interleukin-7 (rhIL7) and bacterial alkaline phosphatase (BAPmut). Methods. The DNA sequences encoding rhIL-7 and BAPmut were subcloned int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bba272f25a65b42b22cd986fcc41aec
https://doi.org/10.7124/feeo.v25.1185
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4
Optimization of the fusion protein rhIL7-BAPmut renaturation process from the Escherichia coli inclusion bodies and its practical application
Autor: M. V. Koval’chuk, M. O. Usenko, D. M. Irodov, O. V. Okunev, O. B. Gorbatiuk, V. A. Kordium, K. I. Bentsionova
Publikováno v: Visnik ukrains'kogo tovaristva genetikiv i selekcioneriv. 17:38-44
Мета. Метою нашої роботи була оптимізація методу ренатурації злитого білка rhIL7-BAPmut, створеного на основі рекомбінантного інтерлейкіну-7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c0772bd23cf6900d13018eb9886062a
https://doi.org/10.7124/visnyk.utgis.17.1.1199
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6
Amazing MSC – phenomenology, problems, solutions and opportunities
Autor: V. A. Kordium, D. M. Irodov
Publikováno v: Biopolymers and Cell, Vol 33, Iss 1, Pp 64-76 (2017)
The review briefly describes the history of prediction and discovery of mesenchymal stem cells (MSCs). The evolution of our views on the nature, functions, and status of MSCs in the organism is presented. We propose that MSCs represent transient stat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942127fa79892abf84b91957d1c3b674
http://biopolymers.org.ua/pdf/33/1/064/
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7
Development of the chromatographic medium for the affinity isolation of the recombinant hIFN-β1b based on immobilized single-chain antibodies
Autor: O. B. Gorbatiuk, D. M. Irodov, M. I. Degtiarova, V. A. Kordium, O. V. Okunev, O. G. Palivoda, Ia. O. Pokholenko
Publikováno v: Biopolymers and Cell, Vol 31, Iss 4, Pp 279-284 (2015)
Aim. The development of a laboratory method for the production of immunoaffinity chromatography medium for the purification of the recombinant human IFN-β1b. Methods. A gene of the chimeric protein ScFvbINF-CBD was constructed using the DNA sequence
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240ea3caf5a413213e7a2397a6c922c6
http://biopolymers.org.ua/pdf/31/4/279/biopolym.cell-2015-31-4-279-en.pdf
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8
Triggering effect of 'therapeutic MSC'
Autor: D. M. Irodov, Yu. B. Chaikovsky, V. A. Kordium
The use of MSCs as a therapeutic agent is proven to be highly successful in many cases. However, the effects obtained are often temporary, and not leading to complete recovery. The reasons of such phenomenon are discussed in the article and the conce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c217692867fd60cc715afb16e7f97c2
http://dspace.nbuv.gov.ua/handle/123456789/153119
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9
Modelling of systemic lesion of organism for development of multitarget cellular and cytokine therapy
Autor: T. P. Gulko, P. V. Buchek, V. A. Kordium, Yu. B. Chaikovsky, A. V. Neverovskiy, M. V. Drahulian, D. M. Irodov, A. Korsak
Publikováno v: Biopolymers and Cell, Vol 32, Iss 5, Pp 381-394 (2016)
In recent decades many human pathologies have taken a chronic course. Modern biology and medicine have come to conceptually new therapeutic approaches. The technologies, comprising stem cells and signaling molecules, are the most promising in this re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417e608464e92fc6a077282b4f059f45
http://dspace.nbuv.gov.ua/handle/123456789/152840
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10
Fundamental biology reached a plateau – development of ideas
Autor: N. S. Shuvalova, D. M. Irodov, V. A. Kordium, T. A. Ruban, V. I. Andrienko, Olga Maslova, E. M. Sukhorada, L. I. Likhachova, S. P. Shpilova
Publikováno v: Biopolymers and Cell, Vol 27, Iss 6, Pp 480-498 (2011)
Scopus-Elsevier
The idea about intracellular transport of metabolic products is presented considering two constituents. The first was described in general in the previous publication. It justified the thesis that cell metabolism is localized and realized not on the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b932828a70f2d2e0384d656f3cb5de9
https://doi.org/10.7124/bc.00011b
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