Výsledky vyhledávání - "D. M. Hammerbeck"

Effects of several glucocorticosteroids and PDE4 inhibitors on increases in total lung eosinophil peroxidase (EPO) levels following either systemic or intratracheal administration in sephadex- or ovalbumin-induced inflammatory models

Autor: D M, Hammerbeck, S M, McGurran, P L, Radziszewski, E A, Egging, D D, Johnson, A M, Hupperts, G W, Gullikson

Publikováno v: Inflammation. 24(4)

Representative glucocorticosteroids (GCS) and phosphodiesterase IV (PDE4) inhibitors were compared in several models of pulmonary inflammation ranging in severity. Lung tissue eosinophil peroxidase (EPO) levels rather than bronchoalveolar lavage flui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1645c9439a93ae17a7a826369f2a234c
https://pubmed.ncbi.nlm.nih.gov/10850854

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Guinea pig pulmonary mechanics: altered sensitivity to carbachol by cadmium and/or selenium

Autor: R. R. Bell, Vani K Nonavinakere, Johnnie L. Early, D. M. Hammerbeck, Magdi R.I. Soliman

Publikováno v: Lung. 176(1)

Male Hartley guinea pigs (480–610 g) were treated intratracheally as follows: saline, cadmium (Cd, 0.3 mg), selenium (Se, 0.3 or 0.06 mg), or Se (0.06 mg) and Cd (0.3 mg) simultaneously. Selenium and Cd were administered as sodium selenite and cadm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b89011c3317e727faf66f47d3b90ae5
https://pubmed.ncbi.nlm.nih.gov/9436174

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Cadmium and/or selenium effects on guinea pig lung PGE2, TXB2 and LTC4

Autor: R R, Bell, M R, Soliman, V K, Nonavinakere, D M, Hammerbeck, J L, Early

Publikováno v: Research communications in molecular pathology and pharmacology. 97(2)

Male Hartley guinea pigs (480-610 g; n=5) were treated intratracheally with saline, cadmium (Cd, 0.3 mg) as cadmium chloride, selenium (Se, 0.3 or 0.06 mg) as sodium selenite or Se (0.06 mg) and Cd (0.3 mg). After 24 hours, lungs were collected and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8aa6ea9a50b61b059d937401a3e091a
https://pubmed.ncbi.nlm.nih.gov/9344235

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The equivalent bronchodilator effects of salbutamol formulated in chlorofluorocarbon and hydrofluoroalkane-134a metered dose inhalers on the histamine-induced pulmonary response in dogs

Autor: M, Nogami-Itoh, I, Yakuo, D M, Hammerbeck, R L, Miller, K, Takeyama

Publikováno v: Pharmaceutical research. 14(2)

The bronchodilator effect of salbutamol formulated in hydrofluoroalkane-134a (HFA-134a), a chlorofluorocarbon (CFC)-free propellant for metered dose inhalation (MDI) devices, was compared with that of salbutamol formulated in CFC in anesthetized dogs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::823b814b1af8a3dc9f717bd0e4bcdb56
https://pubmed.ncbi.nlm.nih.gov/9090711

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Neurally mediated actions of leukotrienes on ion transport in guinea pig distal colon

Autor: D M, Hammerbeck, D R, Brown

Publikováno v: The Journal of pharmacology and experimental therapeutics. 264(1)

The effects of the sulfidopeptide leukotrienes (LT), LTC4, LTD4 and LTE4 on short-circuit current (Isc), a measure of active ion transport, were determined in muscle-stripped mucosa sheets from the guinea pig distal colon. LTC4 and D4, but not E4, ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65ba757daac0fe29bb463113e6ba9b21
https://pubmed.ncbi.nlm.nih.gov/8093730

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Effect of a New Selective 5-Lipoxygenase Inhibitor in Biochemical and Pharmacological Models for the Inhibition of Acute Hypersensitivity Reactions

Autor: M. J. Reiter, A. M. Hupperts, M. A. Rustad, V. L. Stelzer, R. L. Bell, D. M. Hammerbeck, R. A. Scherrer, K. Heghinian, K. F. Swingle

Publikováno v: Annals of the New York Academy of Sciences. 524:398-401

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d57d98eb0e9673a24b85a5fa2e0af64
https://doi.org/10.1111/j.1749-6632.1988.tb38567.x

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The reinforcing properties of procaine and d-amphetamine compared in rhesus monkeys

Autor: D M, Hammerbeck, C L, Mitchell

Publikováno v: The Journal of pharmacology and experimental therapeutics. 204(3)

Twelve rhesus monkeys were studied under a fixed-ratio (FR) schedule of intravenous procaine or d-amphetamine injection from 8 A.M. to 4 P.M. daily. Under the FR schedule, every nth lever press produced an injection. The FR value (n) and the dose per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d7cf3bcc51c23dcb79fae1a29952705
https://pubmed.ncbi.nlm.nih.gov/416198

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Bronchodilator and other pharmacological activities of R-836 (2,5-diethyl-7-(4-thiomorpholino)-1,2,4-triazolo[1,5-c]pyrimidin e)

Autor: K F, Swingle, D M, Hammerbeck, J R, Schmid, V L, Stelzer, M J, Reiter, A M, Peterson, J J, Wade

Publikováno v: Archives internationales de pharmacodynamie et de therapie. 286(2)

The bronchodilator activity of R-386 (2,5-diethyl-7-(4-thiomorpholino)-1,2,4-triazolo[1,5-c]pyrimidine) was demonstrated in isolated guinea-pig tracheal preparations and in vivo in dogs, guinea-pigs and rats. Guinea-pig tracheal preparations contract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2366648572f894ae5ea0db44b6e0db48
https://pubmed.ncbi.nlm.nih.gov/3592866

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