Zobrazeno 1 - 10
of 80
pro vyhledávání: '"D. Logar"'
Autor:
Vita Dolžan, Luis J Leandro-García, Cristina Rodríguez-Antona, D Logar, Lucía Inglada-Pérez, Petra Bohanec Grabar
Publikováno v:
Pharmacogenomics. 13:1583-1594
Aim: We investigated the clinical relevance of SLC19A1 genetic variability for methotrexate (MTX) toxicity in rheumatoid arthritis patients using a haplotype-based approach. Patients & methods: Two hundred and twelve unrelated rheumatoid arthritis pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4afb115ca18ef91ad370bc40642f1f4
https://doi.org/10.2217/pgs.12.150
https://doi.org/10.2217/pgs.12.150
Autor:
Matija Tomšič, Vita Dolzan, Lucija Peterlin Masic, D Logar, Iztok Grabnar, Aleš Mrhar, Blaz Rozman, Daša Šuput, Tina Trdan, Petra Bohanec Grabar
Publikováno v:
Drug Metabolism and Disposition. 37:2061-2068
Leflunomide is a disease-modifying antirheumatic drug used for the treatment of rheumatoid arthritis (RA). Cytochromes P450, mainly CYP1A2 and CYP2C19, may be involved in the transformation of leflunomide to leflunomide metabolite (A77 1726, 2-cyano-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c95e1cb5f211bd680bffc311839811
https://doi.org/10.1124/dmd.109.027482
https://doi.org/10.1124/dmd.109.027482
Autor:
Burkhard F. Leeb, Carlomaurizio Montecucco, J. Rovensky, Judith Sautner, Wolfgang Hueber, Gideon Nesher, I. Andel, Howard A. Bird, M Sonnenblick, D Logar
Publikováno v:
Annals of the Rheumatic Diseases. 62:1189-1194
Objective: To develop response criteria for polymyalgia rheumatica (PMR) for monitoring treatment and comparing alternative treatments regimens. Methods: 76 patients, mean (SD) age 68.7 (7.7) years, were enrolled. Corticosteroids, and non-steroidal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cbb3ed8f09ca0f1e54b7a289244add
https://doi.org/10.1136/ard.2002.002618
https://doi.org/10.1136/ard.2002.002618
Autor:
Z. Domljan, S. Tosi, J. R. Kalden, H. G. Van Den Brink, Marta Mosca, H. Chwalinska-Sadowska, Stefano Bombardieri, R. Fischer, Nada Čikeš, Matthias Schneider, K. Manger, G. Pokorny, Antonio Marchesoni, Attila Kovács, Emese Kiss, H. M. Moutsopoulos, Blaž Rozman, Winfried Graninger, B. Dratwianka, Panayiotis G. Vlachoyiannopoulos, A. Branimir, Josef S. Smolen, Ruud J.T. Smeenk, A. J. G. Swaak, D. Logar, László Kovács
Publikováno v:
Rheumatology. 38:953-958
Objective. Most information available about the disease course of patients with systemic lupus erythematosus (SLE) is restricted to the first 5 yr after disease onset. Data about the disease course 10 yr after disease onset are rare. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1f5835b80e683279876ab77017bdce
https://doi.org/10.1093/rheumatology/38.10.953
https://doi.org/10.1093/rheumatology/38.10.953
Autor:
Saša Čučnik, S. Sodin-Šemrl, D Logar, Gerhard G. Thallinger, Matija Tomšič, Sonja Praprotnik, Tanja Kveder, A. Ambrožič, N Snoj, Katja Perdan-Pirkmajer, Polona Žigon
Publikováno v:
Lupus. 21(2)
Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da05d205f852928cbf8b7516ebad665b
https://pubmed.ncbi.nlm.nih.gov/22235050
https://pubmed.ncbi.nlm.nih.gov/22235050
Autor:
P. Musikic, S. Rupenovic, Franci Demsar, V. Jevtic, M Kos-Golja, I. Watt, D. Logar, Orest Jarh, M. Presetnik, B. Rozman, G. Campion
Publikováno v:
Clinical Radiology. 48:176-181
In an attempt to demonstrate whether clinically selected joints of the hand in active rheumatoid disease had consistent MRI findings, 45 patients were examined, in whom one joint in each was selected by both the referring clinician and patient as bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd9683674cf3c7c5ae85d39f6b67765
https://doi.org/10.1016/s0009-9260(05)80277-6
https://doi.org/10.1016/s0009-9260(05)80277-6
Publikováno v:
Annals of the rheumatic diseases. 68(8)
Leflunomide is a disease-modifying antirheumatic drug used for the treatment of rheumatoid arthritis (RA). Its safety and efficacy was initially described in 1995.1 In vitro studies have demonstrated that CYP1A2 is one of the main leflunomide metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e16579d54671cb0ee72c63546affe9a
https://pubmed.ncbi.nlm.nih.gov/19605743
https://pubmed.ncbi.nlm.nih.gov/19605743
Publikováno v:
Clinical and experimental rheumatology. 27(2)
Glutathione S-transferases (GST); GST-mu1 (GSTM1), GST-pi1 (GSTP1) and GST-theta1 (GSTT1) have peroxidase activity towards cytotoxic metabolites produced in inflammatory reactions, the main feature of rheumatoid arthritis (RA). Genetic polymorphisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17082a3c58707e72aaa6a98ee5c13771
https://pubmed.ncbi.nlm.nih.gov/19473562
https://pubmed.ncbi.nlm.nih.gov/19473562
Publikováno v:
European journal of clinical pharmacology. 64(9)
Leflunomide is a disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA). In vitro studies demonstrated that cytochromes P450 (CYPs), mainly CYP1A2 and CYP2C19, might be involved in leflunomide activation. The aim of our stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b129b606d81dd4825fa3136c0c1c3834
https://pubmed.ncbi.nlm.nih.gov/18496682
https://pubmed.ncbi.nlm.nih.gov/18496682
Publikováno v:
European journal of clinical pharmacology. 64(11)
Methotrexate (MTX) is a disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis (RA). Genetic polymorphisms of reduced folate carrier (RFC1 A80G), P-glycoprotein (MDR1 G2677T>A/C and C3435T), 5,10-methylenetetrahydrofolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c865d00798157813b14cbd435418d6
https://pubmed.ncbi.nlm.nih.gov/18607581
https://pubmed.ncbi.nlm.nih.gov/18607581