Zobrazeno 1 - 10
of 46
pro vyhledávání: '"D. Lemeiter"'
Autor:
C. Clavel, C. Valvason, Liliane Laroche, Marie-Christophe Boissier, T. Begue, D. Lemeiter, Natacha Bessis
Publikováno v:
Human gene therapy. 18(6)
Intraarticular gene transfer with adeno-associated viral (AAV) vectors may allow efficient therapeutic transgene expression within the joint in diseases such as rheumatoid arthritis (RA), allowing high expression of the protein within the joint, prev
Autor:
Gaëlle Clavel, O. Schischmanoff, Luca Semerano, Eric Assier, D. Lemeiter, MC Boissier, Anne Denys
Publikováno v:
Annals of the Rheumatic Diseases. 74:932.2-932
Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality in rheumatoid arthritis (RA). Increased cardiovascular risk in RA is attributed to both traditional risk factors and systemic inflammation over a long period. Limited
Autor:
M.C. deVernejoul, D. Lemeiter, M.C. Boissier, Addolorata Corrado, Martine Cohen-Solal, N. Saidenberg-Kermanac'h
Publikováno v:
Bone. 35(5)
Introduction: Rheumatoid arthritis (RA) is associated with focal and systemic bone loss involving cytokines such as RANKL and TNF-α. RANK-L promotes focal and systemic osteoporosis, whereas osteoprotegerin (OPG) inhibits bone resorption. Although an
Publikováno v:
Annals of the Rheumatic Diseases. 71:483.3-484
Background Interleukin (IL)-35 is a novel interleukin described as an immunosuppressive cytokine specifically produced by CD4+FoxP3+ regulatory T (Tregs) cells but not by conventional T cells. Objectives Since Tregs play a major role in autoimmunity
Publikováno v:
Annals of the Rheumatic Diseases. 71:485.1-485
Background Studies have demonstrated the clinical efficacy of tocilizumab, a humanized anti-IL-6 receptor (R) antibody (Ab), in patients with rheumatoid arthritis (RA). The rational for blocking IL-6 in this disease mainly lays on the pro-inflammator
Autor:
Luca Semerano, Yves-Marie Pers, Allan Thiolat, N Bessis, Pierre Portales, Jerome Biton, D. Lemeiter, Pascale Louis-Plence, Marie-Christophe Boissier, Christian Jorgensen, Patrice Decker
Publikováno v:
Annals of the Rheumatic Diseases. 72:A16.3-A17
Background and Objectives Studies have demonstrated the clinical efficacy of tocilizumab, a humanised anti-IL-6 receptor (R) antibody (Ab), in patients with rheumatoid arthritis (RA). The rational for blocking IL-6 in this disease mainly lays on the
Publikováno v:
Annals of the Rheumatic Diseases. 71:A13.1-A13
Backgroundand objectives Interleukin (IL)-35 is a novel interleukin described as an immunosuppressive cytokine specifically produced by CD4+FoxP3+ regulatory T (Tregs) cells but not by conventional T cells. Since Tregs play a major role in autoimmuni
Publikováno v:
Annals of the Rheumatic Diseases. 71:A6.2-A7
Backgroundand objectives Studies have demonstrated the clinical efficacy of tocilizumab, a humanised anti-IL-6 receptor (R) antibody (Ab), in patients with rheumatoid arthritis (RA). The rational for blocking IL-6 in this disease mainly lays on the p
Autor:
N Bessis, Géraldine Grouard-Vogel, D. Lemeiter, M. A. Laborie, Laure Delavallée, Jérôme Biton, MC Boissier, Luca Semerano
Publikováno v:
Annals of the Rheumatic Diseases. 70:A43-A43
Background and objectives Tumour necrosis factor (TNF) is a critical cytokine in rheumatoid arthritis. The authors recently demonstrated the efficacy of active immunotherapy against TNF (TNF-K) in a human TNF transgenic (TTg) mouse model of arthritis
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