Zobrazeno 1 - 10
of 452
pro vyhledávání: '"D. Laskin"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract The risk of a terrorist attack in the United States has created challenges on how to effectively treat toxicities that result from exposure to chemical weapons. To address this concern, the United States has organized a trans‐agency initia
Externí odkaz:
https://doaj.org/article/757541ea52bd4086b54d42d534ac7d85
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 1, Pp 57-65 (2023)
Abstract Background Sulfur mustard (SM) is a chemical warfare vesicant that severely injures exposed eyes, lungs, and skin. Mechlorethamine hydrochloride (NM) is widely used as an SM surrogate. This study aimed to develop a depilatory double‐disc (
Externí odkaz:
https://doaj.org/article/72a9a0e1fbdc4b48b4fd1ced2485c848
Autor:
Tomas L. Roldan, Shike Li, Christophe Guillon, Ned D. Heindel, Jeffrey D. Laskin, In Heon Lee, Dayuan Gao, Patrick J. Sinko
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 471 (2024)
NDH-4338 is a highly lipophilic prodrug comprising indomethacin and an acetylcholinesterase inhibitor. A design of experiments approach was used to synthesize, characterize, and evaluate the wound healing efficacy of optimized NDH-4338 nanosuspension
Externí odkaz:
https://doaj.org/article/f29f6485c613401fa3d982eecdd727c4
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L345-L357
E-cigarette consumption is under scrutiny by regulatory authorities due to concerns about product toxicity, lack of manufacturing standards, and increasing reports of e-cigarette- or vaping-associated acute lung injury. In vitro studies have demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a944e8f30cce965c1d8accc074094782
https://doi.org/10.1152/ajplung.00222.2022
https://doi.org/10.1152/ajplung.00222.2022
Autor:
L Cody Smith, Andrew J Gow, Elena Abramova, Kinal Vayas, Changjiang Guo, Jack Noto, Jack Lyman, Jessica Rodriquez, Benjamin Gelfand-Titiyevskiy, Callum Malcolm, Jeffrey D Laskin, Debra L Laskin
Publikováno v:
Toxicological Sciences.
Exposure to ozone causes decrements in pulmonary function, a response associated with alterations in lung lipids. Pulmonary lipid homeostasis is dependent on the activity of peroxisome proliferator activated receptor gamma (PPARγ), a nuclear recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1c08c5d07a83c0091743e01396450c
https://doi.org/10.1093/toxsci/kfad048
https://doi.org/10.1093/toxsci/kfad048
Autor:
V. Sunil, K. Vayas, J. Lee, C. Smith, E. Abramova, J. Meshanni, J. Radbel, J. Laskin, D. Laskin
Publikováno v:
B67. ALL THE LUNG'S A STAGE: IMMUNE CELLS ARE THE PLAYERS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c46c83111097456f02992d6eb3cef55
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3995
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3995
Autor:
Simarjot Kaur Sandhu, Suneel Kumar, Jayant Raut, Mandeep Singh, Sandeep Kaur, Garima Sharma, Tomas L. Roldan, Sonia Trehan, Jennifer Holloway, Gabriella Wahler, Jeffrey D. Laskin, Patrick J. Sinko, Francois Berthiaume, Bozena Michniak-Kohn, Praveen Rishi, Narayanan Ganesh, Indu Pal Kaur
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 725 (2021)
The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure homogenization, without using organic solvents, were optimized using the Taguchi de
Externí odkaz:
https://doaj.org/article/4a59475a95674541a5f7864392309f80
Autor:
Peiming Chen, Xiaoping Zhang, Alessandro Venosa, In Heon Lee, Daniel Myers, Jennifer A. Holloway, Robert K. Prud’homme, Dayuan Gao, Zoltan Szekely, Jeffery D. Laskin, Debra L. Laskin, Patrick J. Sinko
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 243 (2020)
Persistent activation of macrophages (MP)s into a proinflammatory M1 or anti-inflammatory M2 phenotype plays a role in several pathological conditions, including autoimmune diseases, fibrosis, infections, atherosclerosis and tumor development. The ma
Externí odkaz:
https://doaj.org/article/aeddc59e9c9f4d83bf8ee6a3d0eb5063
Publikováno v:
Toxicology and applied pharmacology. 455
A characteristic of cytochrome P450 (CYP) enzymes is their ability to generate H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3810ca2ba10fabe4a8bd29c24245da73
https://pubmed.ncbi.nlm.nih.gov/36174671
https://pubmed.ncbi.nlm.nih.gov/36174671
Autor:
Jaclynn A Meshanni, Jordan M Lee, Kinal N Vayas, Rachel Sun, Chenghui Jiang, Grace L Guo, Andrew J Gow, Jeffrey D Laskin, Debra L. Laskin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. :JPET-AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b00d527bda604a39280d3252e158c997
https://doi.org/10.1124/jpet.123.001557
https://doi.org/10.1124/jpet.123.001557