Zobrazeno 1 - 10
of 19
pro vyhledávání: '"D. L. Wolf"'
Publikováno v:
Journal of Biological Chemistry. 268:3048-3051
Factor X is a plasma protein involved in both the intrinsic and extrinsic pathways of blood coagulation. Post-translational modifications of the protein involve gamma-carboxylation of specific glutamic acid residues, beta-hydroxylation of one asparti
Publikováno v:
Journal of Biological Chemistry. 266:13726-13730
Activation of vitamin K-dependent plasma proteases occurs by specific interaction with components of the blood coagulation cascade. In this report, we describe the direct expression and enzymatic characterization of the human coagulation zymogen fact
Autor:
Melvin L. Moeschberger, Frank D. Tice, J S Mohrland, D L Wolf, Carl V. Leier, Philip F. Binkley, Robert J. Cody
Publikováno v:
The American Journal of Cardiology. 65:1361-1367
Twenty-five patients with congestive heart failure (CHF) underwent a double-blind randomized study of the acute hemodynamic effects of orally administered nicorandil, a newly developed vasodilator drug. A dose range of 10 to 60 mg was studied. Nicora
Autor:
M L, Rothenberg, J V, Cox, R F, DeVore, J D, Hainsworth, R, Pazdur, S E, Rivkin, J S, Macdonald, C E, Geyer, J, Sandbach, D L, Wolf, J S, Mohrland, G L, Elfring, L L, Miller, D D, Von Hoff
Publikováno v:
Cancer. 85(4)
This multicenter, Phase II trial was performed to evaluate the antitumor activity and toxicity of irinotecan (CPT-11) in patients with metastatic colorectal carcinoma that had recurred or progressed after 5-fluorouracil (5-FU)-based chemotherapy.CPT-
Publikováno v:
Blood. 86(11)
The plasma clotting factors used to treat hemophiliacs who have developed inhibitory antibodies have a shared history of limited clinical safety and utility. To improve on existing bypass factors, we have developed a reversibly acylated form of human
Publikováno v:
International journal of clinical pharmacology and therapeutics. 32(5)
The effects of nicorandil, a nicotinamide derived vasodilator combining nitrate and potassium channel opener actions, on kidney function have not been determined. This study investigated changes in renal blood flow and glomerular filtration rate as e
Publikováno v:
The Journal of biological chemistry. 268(5)
Factor X is a plasma protein involved in both the intrinsic and extrinsic pathways of blood coagulation. Post-translational modifications of the protein involve gamma-carboxylation of specific glutamic acid residues, beta-hydroxylation of one asparti
Autor:
L J, Fretto, A J, Snape, J E, Tomlinson, J J, Seroogy, D L, Wolf, W J, LaRochelle, N A, Giese
Publikováno v:
The Journal of biological chemistry. 268(5)
The biological effects of platelet-derived growth factor (PDGF) are mediated by cell surface alpha and beta PDGF receptors, which, as a result of ligand binding, undergo dimerization in a manner consistent with PDGF being bivalent. In order to direct
Autor:
J. M. Dugan, Anthony Joseph Antos, E. Murphy, A. J. Price, D. L. Wolf, David K. Smith, Douglas Warren Hall, M. Ramadan
Publikováno v:
Digest of Conference on Optical Fiber Communication.
Increasing demand has caused substantial interest in high bit rate (> 5 Gbit/s) telephony systems, as reflected in emerging use of dispersion-shifted fibers for 1550 nm transmission in new system installations. However, the upgrading of existing stan
Publikováno v:
The Journal of biological chemistry. 266(21)
Activation of vitamin K-dependent plasma proteases occurs by specific interaction with components of the blood coagulation cascade. In this report, we describe the direct expression and enzymatic characterization of the human coagulation zymogen fact