Zobrazeno 1 - 10
of 52
pro vyhledávání: '"D. L. Wickerham"'
Autor:
SL Chia, D L Wickerham, Barry C. Lembersky, Mark L. Graham, James L. Wade, Sandra M. Swain, BT Hennessy, Soonmyung Paik, Charles E. Geyer, Adam Brufsky, Thomas E. Seay, Eleftherios P. Mamounas, SR Dakil, Louis Fehrenbacher, Hanna Bandos, Edward C. McCarron, Gamini S. Soori, Norman Wolmark
Publikováno v:
Cancer Research. 77:S1-05
Background: Extending adjuvant endocrine therapy (tx) after 5 yrs of tamoxifen (Tam) with either Tam or an AI improves disease-free survival (DFS) in early-stage breast cancer (BC). However, optimal duration of adjuvant AI tx beyond 5 yrs is unknown.
Autor:
Hanna Bandos, Worta McCaskill-Stevens, Angela Fagerlin, Therese B. Bevers, D L Wickerham, C. Holmberg, Tracy A. Battaglia
Publikováno v:
Cancer Research. 76:P6-10
Background: Tamoxifen and raloxifene are two selective receptor modulators (SERMs) that have been shown to reduce the risk of developing breast cancer in women at increased risk of the disease. Both drugs are infrequently used in the general U.S. pop
Autor:
Daniel J. Schaid, James N. Ingle, Richard M. Weinshilboum, Celine M. Vachon, Norman Wolmark, Soonmyung Paik, Erin E. Carlson, Yusuke Nakamura, Matthew P. Goetz, D L Wickerham, Liewei Wang, Michiaki Kubo, Fergus J. Couch
Publikováno v:
Cancer Research. 75:P6-10
Purpose: Tamoxifen and raloxifene, are primary prevention strategies for women at high risk of breast cancer (Visvanathan, 2013). Recent advances in genetic studies of breast cancer risk have identified common susceptibility loci that explain 14% of
Autor:
Norman Wolmark, J-H Jeong, Soonmyung Paik, Diana B. Cherbavaz, S-R Kim, FL Baehner, Joseph P. Costantino, Steven M. Butler, S Shak, D L Wickerham, Gong Tang, Qing Liu, Barry C. Lembersky, Eleftherios P. Mamounas, Farid Jamshidian, Amy P. Sing, Thomas B. Julian
Publikováno v:
Cancer Research. 72:S1-10
Background: The RS result predicts outcome in N- and N+, ER+ pts treated with adjuvant endocrine therapy. RS also predicts benefit from adjuvant chemotherapy (CT) and pts with a high RS result receive most of the benefit. We evaluated the association
Autor:
Monika J. Thielen, Craig L. Slingluff, Robert Gray, Daniel J. Sargent, D L Wickerham, Hongkun Wang, Gina R. Petroni, Jacqueline Benedetti, Benjamin Djulbegovic, Anneke T. Schroen, Walter M. Cronin, Xiaofei Wang
Publikováno v:
Clinical Cancer Research. 18:256-262
Purpose: Assessing impact of poor accrual on premature trial closure requires a relevant metric. We propose defining accrual sufficiency on apparent ability to address primary endpoints (PE) rather than attaining accrual targets. Experimental Design:
Autor:
Anneke T. Schroen, D L Wickerham, Benjamin Djulbegovic, Daniel J. Sargent, Xiaofei Wang, Robert Gray, Hongkun Wang, Gina R. Petroni, Jacqueline Benedetti, Monika J. Thielen, Craig L. Slingluff, Wendy F. Cohn, Walter M. Cronin
Publikováno v:
Clinical Trials. 8:591-600
Background Research on barriers to accrual has typically emphasized factors influencing participation after trial activation. Purpose We sought to identify factors influencing trial design and accrual predictions prior to trial activation associated
Autor:
Peter C. Lucas, Zuzana Kos, Sunil Badve, Joseph P. Costantino, Priya Rastogi, Roberto Salgado, Hanna Bandos, Charles E. Geyer, Eleftherios P. Mamounas, Rim S. Kim, Norman Wolmark, Soonmyung Paik, Patrick G. Gavin, Louis Fehrenbacher, Sandra M. Swain, Nan Song, Gert Van den Eynden, Katherine L. Pogue-Geile, Giuseppe Floris, D L Wickerham
Publikováno v:
Journal of Clinical Oncology. 36:12010-12010
12010Background: Stromal tumor infiltrating lymphocytes (sTILs) in HER2-positive and triple-negative breast cancer (BC) are associated with prognosis and treatment response. NSABP B-31 evaluated ch...
Autor:
D L Wickerham, Jong-Hyeon Jeong, B Fisher, Norman Wolmark, Stewart J. Anderson, Eleftherios P. Mamounas, James J. Dignam
Publikováno v:
Scopus-Elsevier
Before 1989, credible information about the treatment of breast cancer was derived mainly from randomized clinical trials that enrolled women with either metastatic (stage IV); locally advanced (stage III); or primary, operable, axillary lymph node-p
Autor:
Elizabeth Tan-Chiu, Maureen T. Kavanah, D L Wickerham, Steven E. Reis, Joseph P. Costantino, Jiping Wang
Publikováno v:
JNCI Journal of the National Cancer Institute. 93:16-21
Background The overall effect of prophylactic tamoxifen in women depends on the balance between the effects of the drug, which include preventing breast cancer and altering cardiovascular risk. In a recent clinical trial, postmenopausal estrogen-prog
Autor:
James J. Dignam, D L Wickerham, Linda H. Colangelo, Roy E. Smith, J Jones, Norman Wolmark, Wei Tian
Publikováno v:
JNCI Journal of the National Cancer Institute. 91:1933-1940
Background: African-Americans generally have lower survival rates from colon cancer than Caucasian Americans. This disparity has been attributed to many sources, including diagnosis at later disease stage and other unfavorable disease features, inade