Výsledky vyhledávání - "D. L. Raunig"

Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs

Autor: Frederick R. Nelson, Kari Schmidt, Katrina L. Mealey, D. K. Waiting, D. L. Raunig

Publikováno v: Journal of Veterinary Pharmacology and Therapeutics. 33:453-460

Mealey, K.L., Waiting, D., Raunig, D.L., Schmidt, K.R., Nelson, F.R. Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs. J. vet. Pharmacol. Therap. 33, 453–460. Previous studies have indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b3e1b5de80da911c279fe391e7146cc
https://doi.org/10.1111/j.1365-2885.2010.01170.x

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Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs

Autor: K L, Mealey, D, Waiting, D L, Raunig, K R, Schmidt, F R, Nelson

Publikováno v: Journal of veterinary pharmacology and therapeutics. 33(5)

Previous studies have indicated that intestinal P-glycoprotein (P-gp) limits the oral bioavailability of substrate drugs and alters systemic pharmacokinetics. In this study, dogs lacking functional P-gp were used to determine the contribution of P-gp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e6eca268095e0bbf2c2cce6f6a9e6a96
https://pubmed.ncbi.nlm.nih.gov/20840389

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