Zobrazeno 1 - 10 of 23 pro vyhledávání: '"D. L. Mayers"'
1
Intact antigen receptor-mediated calcium signals in patients with early stage HIV-1 infection
Autor: T E Hickey, P J Blair, S Perfetto, D S Smoot, K F Wagner, D C St Louis, D L Mayers, J N Siegel, C H June
Publikováno v: The Journal of Immunology. 156:4012-4017
A variety of deficiencies in T cell activation have been described in HIV-1 infection. To determine whether one component of Ag receptor signal transduction might be impaired and contribute to the immunopathology of HIV infection, we tested CD4 cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a90783ba1e622e667c2abf636bb342a0
https://doi.org/10.4049/jimmunol.156.10.4012
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2
Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates
Autor: Edward Arnold, Holly Bazmi, R. F. Schinazi, J. Weir, D. L. Mayers, John W. Mellors, Y. Hsiou, B. M. Roy
Publikováno v: Antimicrobial Agents and Chemotherapy. 39:1087-1092
Foscarnet (phosphonoformic acid) is a pyrophosphate analog that inhibits the replication of human immunodeficiency virus type 1 (HIV-1) in vitro and in patients with AIDS. HIV-1 resistance to foscarnet has not been reported despite long-term foscarne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4315cf9786be946ecfc061d3c706ca
https://doi.org/10.1128/aac.39.5.1087
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3
Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates
Autor: Daniel R. Kuritzkes, S A Fiscus, J M Arduino, D L Mayers, P S Reichelderfer, A. J. Japour
Publikováno v: Journal of Clinical Microbiology. 32:2291-2294
A standardized assay in 96-well microtiter plates for syncytium-inducing (SI) human immunodeficiency virus type 1 phenotype detection using MT-2 cells has been developed. SI variants were found in 67% of the patients with advanced human immunodeficie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f6c121f968341d8d7ed70c10bb3cb6
https://doi.org/10.1128/jcm.32.9.2291-2294.1994
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4
Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates. The RV-43 Study Group, the AIDS Clinical Trials Group Virology Committee Resistance Working Group
Autor: Daniel R. Kuritzkes, Richard T. D'Aquila, R J Black, D L Mayers, Laurel A. Beckett, J M Arduino, Victoria A. Johnson, Anthony J. Japour, Patricia Reichelderfer, J Lane
Publikováno v: Antimicrobial Agents and Chemotherapy. 37:1095-1101
A standardized antiviral drug susceptibility assay for clinical human immunodeficiency virus type 1 (HIV-1) isolates has been developed for use in clinical trials. The protocol is a two-step procedure that first involves cocultivation of patient infe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba137565ccff89ebaa853ad5e361f58
https://doi.org/10.1128/aac.37.5.1095
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5
Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virus
Autor: D. L. Mayers, Ladislau C. Kovari, C. A. Holland-Staley, Edward M. Golenberg, Kevin J. Pobursky
Publikováno v: Archives of virology. 147(7)
The N-terminal one-third of the hepatitis C virus nonstructural gene 3 (NS3) codes for a serine protease. To investigate natural genetic diversity of this enzyme a nested PCR reaction was developed to obtain NS3 protease sequence data directly from p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ecafff50d4b4eb8e84e8c7194bc7a8
https://pubmed.ncbi.nlm.nih.gov/12111414
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6
A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS
Autor: J D, Baxter, D L, Mayers, D N, Wentworth, J D, Neaton, M L, Hoover, M A, Winters, S B, Mannheimer, M A, Thompson, D I, Abrams, B J, Brizz, J P, Ioannidis, T C, Merigan
Publikováno v: AIDS (London, England). 14(9)
To determine the short-term effects of using genotypic antiretroviral resistance testing (GART) with expert advice in the management of patients failing on a protease inhibitor and two nucleoside reverse transcriptase inhibitors.Prospective randomize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbd9d9d9e01b70ac863d95a121972a39
https://pubmed.ncbi.nlm.nih.gov/10894268
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7
Frequency of antiretroviral drug resistance mutations in HIV-1 strains from patients failing triple drug regimens. The Terry Beirn Community Programs for Clinical Research on AIDS
Autor: M A, Winters, J D, Baxter, D L, Mayers, D N, Wentworth, M L, Hoover, J D, Neaton, T C, Merigan
Publikováno v: Antiviral therapy. 5(1)
The frequency of protease and reverse transcriptase (RT) gene mutations was determined in HIV-1 strains from 153 patients entering the CPCRA 046 (GART) study who were failing triple-drug regimens consisting of one protease inhibitor (PI) and two RT i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14f6c24d5a8c1e93afbf575507cbb023
https://pubmed.ncbi.nlm.nih.gov/10846594
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8
Exotic virus infections of military significance. Hemorrhagic fever viruses and pox virus infections
Autor: D L, Mayers
Publikováno v: Dermatologic clinics. 17(1)
Military personnel are frequently deployed to distant locations around the world under conditions of great stress, which involve potential exposure to hazardous viruses that are not commonly seen in the developed world. This article will provide an o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44f710bcdbd773460bc8313805990631
https://pubmed.ncbi.nlm.nih.gov/9986994
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9
Size and duration of zidovudine benefit in 1003 HIV-infected patients: U.S. Army, Navy, and Air Force natural history data. Military Medical Consortium for Applied Retroviral Research
Autor: L I, Gardner, S H, Harrison, C W, Hendrix, S P, Blatt, K F, Wagner, R C, Chung, R W, Harris, D L, Cohn, D S, Burke, D L, Mayers
Publikováno v: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 17(4)
The study's objectives were to determine the size and duration of benefits of early versus delayed versus late treatment with zidovudine (ZDV) on disease progression and mortality in HIV-infected patients, and whether patients rapidly progressing bef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9456b9e3f197abd8aa3dbcf7b94e1da5
https://pubmed.ncbi.nlm.nih.gov/9525436
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10
Measurement of CD69 induction in the assessment of immune function in asymptomatic HIV-infected individuals
Autor: S P, Perfetto, T E, Hickey, P J, Blair, V C, Maino, K F, Wagner, S, Zhou, D L, Mayers, D, St Louis, C H, June, J N, Siegel
Publikováno v: Cytometry. 30(1)
Peripheral blood mononuclear cells from many asymptomatic HIV-infected patients exhibit defects in cytokine production and impaired proliferative responses in vitro but the mechanisms underlying this subclinical immune deficiency are controversial. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afafccbde1b0beceaa014b8142d87f77
https://pubmed.ncbi.nlm.nih.gov/9056736
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