Zobrazeno 1 - 10 of 12 pro vyhledávání: '"D. L. Heald"'
1
The Effect of Scatter and Attenuation on Aerosol Deposition as Determined by Gamma Scintigraphy
Autor: D L Heald, Zhenghong Lee, A D Nelson, Marc S. Berridge
Publikováno v: Journal of Aerosol Medicine. 14:167-183
Gamma scintigraphy is often used to quantify deposition patterns from aerosol inhalers. The errors caused by scatter and tissue attenuation in planar Tc-99m gamma scintigraphy were investigated based on the data collected from four subjects in this s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a00447776e842f389b05d017a22478a
https://doi.org/10.1089/08942680152484108
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2
Pulmonary distribution and kinetics of inhaled [11C]triamcinolone acetonide
Autor: M S, Berridge, Z, Lee, D L, Heald
Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(10)
Triamcinolone acetonide (TAA) is an anti-inflammatory steroid used for topical treatment of allergic rhinitis and asthma. Drug deposition onto target tissues is an important parameter, so methods for accurate deposition measurement are needed. Lung d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67b6ea6c559a0a7cc340ac02d55e79ba
https://pubmed.ncbi.nlm.nih.gov/11037987
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3
Biodistribution and kinetics of nasal carbon-11-triamcinolone acetonide
Autor: M S, Berridge, D L, Heald, G J, Muswick, G P, Leisure, K W, Voelker, F, Miraldi
Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(11)
PET is a technique with a strong potential for use in drug evaluation and development. In particular, the distribution and pharmacokinetics of locally administered drugs may be advantageously explored noninvasively using labeled compounds. This pilot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db93faf46bd2f15266db8f8281e35077
https://pubmed.ncbi.nlm.nih.gov/9829591
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4
Gastric emptying and the pharmacokinetics of the cephalosporin antibiotic, cefpodoxime proxetil
Autor: G S, Hughes, D L, Heald, R, Patel, C R, Spillers, D H, Batts, A R, Euler
Publikováno v: Methods and findings in experimental and clinical pharmacology. 12(3)
The effects of gastric motility on the pharmacokinetics of cefpodoxime proxetil, an oral, broad spectrum, third-generation cephalosporin antibiotic were evaluated in 12 healthy subjects. In this open-label, crossover trial, each subject took a 200 mg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b76e7be1f4c50c7cea33e71ab264f0af
https://pubmed.ncbi.nlm.nih.gov/2352449
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5
Uptake and distribution of lidocaine in fetal lambs
Autor: Robert Bettinger, J. U. Bell, Dinesh Doshi, D. L. Heald, Yadin David, Richard P. Miller, M. J. Kennedy, Roland L. Kennedy, Hansel de Sousa
Publikováno v: Anesthesiology. 72(3)
The fetal uptake of lidocaine was measured continually and quantitatively during and after a constant rate intravenous (iv) maternal infusion into five chronically prepared pregnant ewes. Lidocaine, 6 mg/kg (base), was infused at a constant rate for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2954ba8dd1ade0247004175387d380e
https://pubmed.ncbi.nlm.nih.gov/2310029
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7
Laboratory Experiment in Semiconductor Surface-Field Effects
Autor: D. L. Heald, F. R. Goodman, R. C. Neville
Publikováno v: American Journal of Physics. 42:572-579
A laboratory instructional program involving metal-insulator-semiconductor (MIS) devices is described. At the University of California, Santa Barbara (UCSB), this program has been used to teach the theory and applications of semiconductor surface fie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3298f69723c4f9de421c002f4f3c56a2
https://doi.org/10.1119/1.1987778
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8
Uptake and Distribution of Bupivacaine in Fetal Lambs
Autor: Dinesh Doshi, M. J. Kennedy, Richard R. Miller, Roland L. Kennedy, Hansel deSousa, Yadin David, D. L. Heald, J. U. Bell
Publikováno v: Anesthesiology. 65:247-253
Direct continual measurement of placental drug transfer was introduced to evaluate more precisely the fetal uptake of a commonly used local anesthetic in obstetrics. Bupivacaine, 2.7 mg X kg-1 (base), was infused at a constant rate over 1 h into a ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03308f6c6265241f95dd7c3f87cfe0ed
https://doi.org/10.1097/00000542-198609000-00002
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9
Uptake and distribution of bupivacaine in fetal lambs
Autor: R L, Kennedy, R P, Miller, J U, Bell, D, Doshi, H, deSousa, M J, Kennedy, D L, Heald, Y, David
Publikováno v: Anesthesiology. 65(3)
Direct continual measurement of placental drug transfer was introduced to evaluate more precisely the fetal uptake of a commonly used local anesthetic in obstetrics. Bupivacaine, 2.7 mg X kg-1 (base), was infused at a constant rate over 1 h into a ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9bc0f3421c3beeefa0aab25de6da644
https://pubmed.ncbi.nlm.nih.gov/3752568
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