Výsledky vyhledávání - "D. L. Fairclough"

Evaluation of quality of life in a clinical trial with nonrandom dropout: the effect of epoetin alfa in anemic cancer patients

Autor: D L, Fairclough, D D, Gagnon, M J, Zagari, N, Marschner, M, Dicato

Publikováno v: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 12(8)

Quality of life (QOL) endpoints from a randomized, placebo-controlled trial of anemic cancer patients treated with nonplatinum-containing chemotherapy who received epoetin alfa or placebo were subjected to a sensitivity analysis. Three QOL instrument

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11555a2d1f51cda5639c99e16cf51b34
https://pubmed.ncbi.nlm.nih.gov/14651419

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Quality of life and quality adjusted survival for breast cancer patients receiving adjuvant therapy. Eastern Cooperative Oncology Group (ECOG)

Autor: D L, Fairclough, J H, Fetting, D, Cella, W, Wonson, C M, Moinpour

Publikováno v: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 8(8)

The objective was to compare health related quality of life (QOL) in hormone receptor negative, node-positive breast cancer patients receiving adjuvant chemotherapy to determine whether a more intensive chemotherapy regimen has an adverse effect upon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b407f167eff9c7db7a0e2c71757200af
https://pubmed.ncbi.nlm.nih.gov/10855346

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Autor: L B, Wenzel, D L, Fairclough, M J, Brady, D, Cella, K M, Garrett, B C, Kluhsman, L A, Crane, A C, Marcus

Publikováno v: Cancer. 86(9)

The objective of this study was to compare the quality of life (QOL) of younger (or =50 years) versus older (50 years) women on recent completion of treatment of breast carcinoma.Data reported herein were obtained from a baseline assessment of 304 br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::088266984ba524b8f338ffc185f625ee
https://pubmed.ncbi.nlm.nih.gov/10547550

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A test strip for diamines in tuna

Autor: M, Hall, P A, Sykes, D L, Fairclough, L J, Lucchese, P, Rogers, W, Staruszkiewicz, R C, Bateman

Publikováno v: Journal of AOAC International. 82(5)

This study describes the production of a solid-phase assay (test strip/dipstick test) for putrescine and cadaverine in tuna based on the coupling of an amine oxidase to a peroxidase/dye system. The assay was linear to 75 microM in phosphate buffer, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::624098b77dbb6f3072d30b33f9ed07e1
https://pubmed.ncbi.nlm.nih.gov/10513011

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Missing data in quality of life research in Eastern Cooperative Oncology Group (ECOG) clinical trials: problems and solutions

Autor: E A, Hahn, K A, Webster, D, Cella, D L, Fairclough

Publikováno v: Statistics in medicine. 17(5-7)

Incorporation of quality of life (QOL) investigation into Eastern Cooperative Oncology Group (ECOG) multi-centre clinical trials has led to innovative strategies for protocol design and high quality data collection. A scientific advisory committee re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13afe4cd3c4803124c53d9aab9f492c0
https://pubmed.ncbi.nlm.nih.gov/9549804

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Why are missing quality of life data a problem in clinical trials of cancer therapy?

Autor: D L, Fairclough, H F, Peterson, V, Chang

Publikováno v: Statistics in medicine. 17(5-7)

Assessment of health related quality of life has become an important endpoint in many cancer clinical trials. Because the participants of these trials often experience disease and treatment related morbidity and mortality, non-random missing assessme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a189d019ca59e4314723c682b759f65
https://pubmed.ncbi.nlm.nih.gov/9549815

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Statistical analysis of quality of life with missing data in cancer clinical trials

Autor: A B, Troxel, D L, Fairclough, D, Curran, E A, Hahn

Publikováno v: Statistics in medicine. 17(5-7)

We summarize issues that arise when considering quality of life (QOL) data in cancer clinical trials, especially those related to missing data. We describe different types of missing data mechanisms, and discuss ways of assessing and testing missing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05f2cdc97a53493698e38583a2064a17
https://pubmed.ncbi.nlm.nih.gov/9549814

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Summary measures and statistics for comparison of quality of life in a clinical trial of cancer therapy

Autor: D L, Fairclough

Publikováno v: Statistics in medicine. 16(11)

Assessment of health related quality of life (QOL) has become an important endpoint in many clinical trials of cancer therapy. Most of these studies entail multiple QOL scales that are assessed repeatedly over time. As a result, the problem of multip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f11243caa290382e3b79b09eb2834d60
https://pubmed.ncbi.nlm.nih.gov/9194267

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