Zobrazeno 1 - 10
of 34
pro vyhledávání: '"D. L. Dillehay"'
Autor:
E M, Schmelz, P C, Roberts, E M, Kustin, L A, Lemonnier, M C, Sullards, D L, Dillehay, A H, Merrill
Publikováno v:
Cancer research. 61(18)
Sphingolipid consumption suppresses colon carcinogenesis, but the specific genetic defect(s) that can be bypassed by these dietary components are not known. Colon tumors often have defect(s) in the adenomatous polyposis coli (APC)/beta-catenin regula
Publikováno v:
Contemporary topics in laboratory animal science. 39(5)
Three days after an uneventful parturition, a Brittany spaniel/beagle puppy (Canis familiaris) was nursing but not gaining weight as rapidly as were its littermates. Although its diet was supplemented, the puppy died 10 days after birth. The renal pe
Publikováno v:
Laboratory animal science. 49(6)
This study was conducted to compare various strategies for insulin replacement therapy in the streptozotocin-induced diabetic rat model.Control and diabetic Sprague Dawley rats were fed ad libitum, blood glucose concentration was measured twice daily
Publikováno v:
The American journal of pathology. 156(1)
Despite recent advances in diagnosis and treatment of testicular cancer, its causes remain unknown. The most common conditions known to be associated with testicular cancer are cryptorchidism, infertility, and overexposure to pesticides or radiation.
Publikováno v:
Cancer research. 59(22)
Dietary sphingolipids inhibit chemically induced colon cancer in mice. The most likely mediators of this effect are the metabolites ceramide (Cer) and sphingosine, which induce growth arrest and apoptosis in transformed cells. Sphingolipids are diges
Publikováno v:
Cancer research. 56(21)
Sphingolipids are hydrolyzed in the gastrointestinal tract to ceramide, sphingosine, and other metabolites that can modulate cell growth, differentiation, and apoptosis. To characterize the effects of dietary sphingolipids on colon carcinogenesis, fe
Publikováno v:
Laboratory animal science. 46(4)
Autor:
R R, Tekmal, N, Ramachandra, S, Gubba, V R, Durgam, J, Mantione, K, Toda, Y, Shizuta, D L, Dillehay
Publikováno v:
Cancer research. 56(14)
Our recent studies have shown that the cellular gene at the mouse mammary tumor virus integration site in the int-5 locus is aromatase. To study the role of int-5/aromatase in normal mammary development and mammary neoplasia, we have generated transg
Publikováno v:
The Prostate. 28(1)
To develop an improved model of human prostate cancer, 16-wk-old Wistar rats were treated orally for 18 days with the antiandrogen, flutamide (50 mg/kg body weight [BW]/day), followed by 3 days of s.c. testosterone (100 mg/kg BW). There were the only
Publikováno v:
Laboratory animal science. 45(6)
A new species of mycoplasmas was isolated from the lungs and nasopharyngeal washings of prairie voles (Microtus ochrogaster). Clinical signs of disease and microscopic lesions were not observed at the time of this isolation. The organism was cultured