Výsledky vyhledávání - "D. L. Chapman"

Quantitative Evaluation of Leukocyte Infiltration into the Spinal Cord in a Model of Experimental Autoimmune Encephalomyelitis: Statistical-Analytical Techniques for Use in Evaluating Drugs

Autor: K. A. Ready, S. M. Vroegop, L. A. Galinet, S. E. Buxser, D. L. Chapman, C. J. Dunn, T. J. Vidmar

Publikováno v: International Journal of Immunopathology and Pharmacology. 11:117-137

Experimental autoimmune encephalomyelitis (EAE) is considered a useful animal model for preclinical development of drugs to treat human multiple sclerosis. The relationship between clinical disease signs and leukocyte infiltration into the lower spin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c94a3fc0ca06e15dda74bfded2ac278
https://doi.org/10.1177/039463209801100302

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Regulation of expression of IL-1 receptor antagonist protein in human synovial and dermal fibroblasts

Autor: R F Krzesicki, C A Hatfield, M J Bienkowski, J C McGuire, G E Winterrowd, D L Chapman, A E Berger, R N McEwan, D B Carter, J G Chosay

Publikováno v: The Journal of Immunology. 150:4008-4018

The IL-1R antagonist protein (IRAP) is a competitive inhibitor of IL-1, which is predominantly synthesized by monocytes. We show that this molecule is also expressed in human synovial fibroblasts and dermal fibroblasts (CRL 1445). IRAP mRNA was regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe05f72949b21a5239f7dc50511eefa8
https://doi.org/10.4049/jimmunol.150.9.4008

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IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium

Autor: G S Firestein, A E Berger, D E Tracey, J G Chosay, D L Chapman, M M Paine, C Yu, N J Zvaifler

Publikováno v: The Journal of Immunology. 149:1054-1062

IL-1 can participate in the perpetuation of arthritis through direct stimulation of synoviocytes and augmentation of matrix degradation. Hence, local production of the IL-1R antagonist protein (IRAP) might be an important negative feedback signal tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::183570b0f9247d8e98ec6159681392df
https://doi.org/10.4049/jimmunol.149.3.1054

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Eliminating sleep-associated hypoxemia improves growth in infants with bronchopulmonary dysplasia

Autor: L J, Moyer-Mileur, D W, Nielson, K D, Pfeffer, M K, Witte, D L, Chapman

Publikováno v: Pediatrics. 98(4 Pt 1)

Infants with bronchopulmonary dysplasia (BPD) have been previously reported to have a decrease in growth velocity after stopping supplemental oxygen (SO). SO was stopped after a short-term recording (20-30 minutes) of pulse oxygen saturation (Sao2) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::405ed287d4ba75de56fdbee7d2b16f09
https://pubmed.ncbi.nlm.nih.gov/8885961

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Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development

Autor: D L, Chapman, N, Garvey, S, Hancock, M, Alexiou, S I, Agulnik, J J, Gibson-Brown, J, Cebra-Thomas, R J, Bollag, L M, Silver, V E, Papaioannou

Publikováno v: Developmental dynamics : an official publication of the American Association of Anatomists. 206(4)

A novel family of genes, characterized by the presence of a region of homology to the DNA-binding domain of the Brachyury (T) locus product, has recently been identified. The region of homology has been named the T-box, and the new mouse genes that c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e34e7dec3b253fac61d9471dc5b354e
https://pubmed.ncbi.nlm.nih.gov/8853987

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Expression of proliferating cell nuclear antigen in the mouse germ line and surrounding somatic cells suggests both proliferation-dependent and -independent modes of function

Autor: D L, Chapman, D J, Wolgemuth

Publikováno v: The International journal of developmental biology. 38(3)

The distribution of proliferating cell nuclear antigen (PCNA) in specific somatic and germ cells of the adult mouse ovary and testis was assessed using immunocytochemical staining and immunoblot analysis and was correlated with cellular proliferation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af19e041ff0c5bed99ddf27184bd0747
https://pubmed.ncbi.nlm.nih.gov/7848832

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Ion transport regulation of lung liquid secretion in foetal lambs

Autor: D P, Carlton, J J, Cummings, D L, Chapman, F R, Poulain, R D, Bland

Publikováno v: Journal of developmental physiology. 17(2)

To test the hypothesis that liquid formation in the foetal lung reflects the balance between Cl- secretion and Na+ absorption by the respiratory tract epithelium, we studied the independent and combined effects of selective ion transport inhibitors o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a4680385788837172b89a2baf0c87d0
https://pubmed.ncbi.nlm.nih.gov/1500638

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VI. On the rate of explosion in gases

Autor: D. L. Chapman

Publikováno v: The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science. 47:90-104

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3d1379ccedc41e8b2416aa422d9d10
https://doi.org/10.1080/14786449908621243

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