Zobrazeno 1 - 10
of 41
pro vyhledávání: '"D. L. Butler"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:5747-5760
GSK1322322 is a peptide deformylase inhibitor active against Staphylococcus aureus strains resistant to currently marketed antibiotics. Our aim was to assess the activity of GSK1322322 against intracellular S. aureus using an in vitro pharmacodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d309fbb66c95869d36d153c056c1957
https://doi.org/10.1128/aac.00827-15
https://doi.org/10.1128/aac.00827-15
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:707-710
GSK1322322, a novel peptide deformylase inhibitor currently in development as an oral and intravenous agent for the treatment of hospitalized community-acquired bacterial pneumonia, showed poor in vitro activity against a panel of 50 Legionella pneum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbe7d26938affbd7ced50e1f771ddb0
https://doi.org/10.1128/aac.04006-14
https://doi.org/10.1128/aac.04006-14
Autor:
Aubart Kelly M, Karen O'Dwyer, Dongzhao Chen, Thomas Lewandowski, Magdalena Zalacain, D. L. Butler
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:290-296
Peptide deformylase (PDF), a clinically unexploited antibacterial target, plays an essential role in protein maturation. PDF inhibitors, therefore, represent a new antibiotic class with a unique mode of action that provides an alternative therapy for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb52a083395b0bc2cf01a74328e0650c
https://doi.org/10.1128/aac.01292-13
https://doi.org/10.1128/aac.01292-13
Autor:
B. Johnson, Daryl J. Hoban, J. A. Poupard, Samuel K. Bouchillon, Linda A. Miller, D. L. Butler, J. Johnson, Kay A. Saunders
Publikováno v:
International Journal of Antimicrobial Agents. 23:181-196
This study was a multi-centre, multi-country surveillance of 27,247 Gram-positive and Gram-negative isolates collected from 131 study centres in 44 countries from 1997 to 2000. MICs of gemifloxacin were compared with penicillin, amoxicillin-clavulani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181e7dc8b8ace0509a8dfcb4f684a6c0
https://doi.org/10.1016/j.ijantimicag.2003.08.006
https://doi.org/10.1016/j.ijantimicag.2003.08.006
Autor:
Daryl J. Hoban, Samuel K. Bouchillon, Linda A. Miller, J. A. Poupard, D. L. Butler, James A. Karlowsky, John L. Johnson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:3008-3011
From 1997 to 1999, 94 study centers in 15 European, 3 North American, and 2 South American countries contributed 2,632 isolates of Streptococcus pneumoniae to an international antimicrobial susceptibility testing study. Only 62.0% of isolates were su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eeb17df0bce08dbf22c1bb19705cebc
https://doi.org/10.1128/aac.44.11.3008-3011.2000
https://doi.org/10.1128/aac.44.11.3008-3011.2000
Autor:
David Felmingham, D. L. Butler, R. C. Gagnon, J. A. Poupard, Linda A. Miller, R. N. Grüneberg
Publikováno v:
Journal of Antimicrobial Chemotherapy. 43:777-782
A number of published studies have shown that the MICs of amoxycillin and/or co-amoxyclav are lower than those of ampicillin and/or penicillin for Streptococcus pneumonlae. Other published studies have concluded that the activities of amoxycillin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8e401390c564343a22609a7f4c9365
https://doi.org/10.1093/jac/43.6.777
https://doi.org/10.1093/jac/43.6.777
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:283-286
Current National Committee for Clinical Laboratory Standards (NCCLS) susceptibility guidelines for quality control testing with Haemophilus influenzae do not include a β-lactamase-producing strain that could detect the deterioration of the β-lactam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacabdc4cb88a55ff2cc7b0729181f4c
https://doi.org/10.1128/aac.43.2.283
https://doi.org/10.1128/aac.43.2.283
Autor:
Donghui Qin, Meredith Hackel, Aubart Kelly M, Sarah Hightower, Karen O'Dwyer, D. L. Butler, Daryl J. Hoban, Magdalena Zalacain, Samuel K. Bouchillon
Publikováno v:
Antimicrobial agents and chemotherapy. 57(5)
GSK1322322 is a novel peptide deformylase (PDF) inhibitor being developed for the intravenous and oral treatment of acute bacterial skin and skin structure infections and hospitalized patients with community-acquired pneumonia. The activity of GSK132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8300a25112804e5df4b65dbce6152429
https://pubmed.ncbi.nlm.nih.gov/23478958
https://pubmed.ncbi.nlm.nih.gov/23478958
Autor:
Kay A. Saunders, George G. Zhanel, J. Johnson, Daryl J. Hoban, D. L. Butler, Samuel K. Bouchillon, J. A. Poupard, Linda A. Miller
Publikováno v:
International journal of antimicrobial agents. 21(5)
The in vitro activity of amoxycillin-clavulanic acid was compared with four comparator oral antimicrobial agents; ampicillin, azithromycin, cefuroxime and trimethoprim-sulphamethoxazole against 4536 recent clinical isolates covering 29 species isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee75087798d70d6023367414aacc8b75
https://pubmed.ncbi.nlm.nih.gov/12727075
https://pubmed.ncbi.nlm.nih.gov/12727075
Publikováno v:
Clinical orthopaedics and related research.
Articular cartilage shows little or no intrinsic capacity for repair in response to injury or disease, and even minor lesions or injuries may lead to progressive damage and joint degeneration. Tissue engineering is a relatively new but rapidly growin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd9ea12bd8388282b16b1b575a2184f9
https://pubmed.ncbi.nlm.nih.gov/11603713
https://pubmed.ncbi.nlm.nih.gov/11603713