Zobrazeno 1 - 10
of 77
pro vyhledávání: '"D. Kristol"'
Publikováno v:
Journal of Molecular Recognition. 7:211-214
An 'active analog' approach to receptor mapping was used to identify a pharmacophore for a set of thymidine nucleoside analog inhibitors of HIV-1 reverse transcriptase. The preliminary results indicate that the O2, O4', and O5' atoms are capable of a
Publikováno v:
Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005..
Endotoxin (Lipopolysaccharide, LPS) is a part of the outer membrane of the cell wall of gram-negative bacteria. LPS induces activation of the coagulation cascade in humans. This procoagulant effect on citrated whole blood produces a shortened clottin
Publikováno v:
IEEE 30th Annual Northeast Bioengineering Conference, 2004. Proceedings of the.
The effect of copper ions on the blood coagulation time was determined. In the experiment that was performed in vitro, there were three different aliquots for each blood sample. The three aliquots were composed of the control, 0.05 mM CuSO/sub 4/, an
Publikováno v:
IEEE 30th Annual Northeast Bioengineering Conference, 2004. Proceedings of the.
Tissue factor (TF) is a transmembrane glycoprotein and the main triggering element for blood coagulation. Expression of TF on the cell surfaces and its appearance as a soluble molecule are characteristic features of acute and chronic inflammation in
Publikováno v:
IEEE 30th Annual Northeast Bioengineering Conference, 2004. Proceedings of the.
Clinically, the dissolution of pathologic blood clots through conventional therapeutics may alter patient coagulation profile and increase risk of thrombohaemorrhagic complications. We developed an in vitro model to determine the effect of soluble cl
Publikováno v:
IEEE 30th Annual Northeast Bioengineering Conference, 2004. Proceedings of the.
Silver ion, a potent antimicrobial and procoagulant, is hypothesized to achieve its haemostatic effect by binding anticoagulant proteins. We performed in vitro studies to gain more insight into its mechanism of action. 10 /spl mu/L of 5% AgNO/sub 3/
Publikováno v:
2003 IEEE 29th Annual Proceedings of Bioengineering Conference.
Streptokinase (SK) therapy has become a common clinical intervention in the treatment of acute coronary syndromes. Recent clinical trials indicate that adjuvant treatment with low molecular weight heparin (LMWH) or bivalirudin (BV) may attenuate fibr
Publikováno v:
2003 IEEE 29th Annual Proceedings of Bioengineering Conference.
Protamine sulfate (protamine), a low molecular weight poly-cationic amine, has been used for some time on patients undergoing cardiac operations and procedures. It is particularly used on patients who have been treated with heparin (an anticoagulant)
Publikováno v:
2003 IEEE 29th Annual Proceedings of Bioengineering Conference.
The sedimentation rate (sed rate), also called, the Erythrocyte Sedimentation Rate (ESR) is a blood test for inflammation in the body. If it is elevated, then there is an inflammatory process in the body which can be monitored. The test is broad and
Publikováno v:
2003 IEEE 29th Annual Proceedings of Bioengineering Conference.
The benefits of intensive insulin therapy for type 2 diabetics with cardiovascular disease (CVD) are highly controversial. We performed in vitro studies to determine whether insulin has any effect on whole blood coagulation and assess how insulin res