Zobrazeno 1 - 10
of 31
pro vyhledávání: '"D. Kiderlen"'
Publikováno v:
Biochemical Pharmacology. 69:1853-1867
The potential of pyridinium-4-aldoximes, such as obidoxime, to reactivate diethylphosphorylated acetylcholinesterases is not fully exploited due to the inevitable formation of phosphoryloximes (POX) with high anticholinesterase activity. Mono(diethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac128a15869883caf9e4aee44cf2f836
https://doi.org/10.1016/j.bcp.2005.04.003
https://doi.org/10.1016/j.bcp.2005.04.003
Publikováno v:
Archives of Toxicology. 74:27-32
The potential of obidoxime and other pyridinium-4-aldoximes to reactivate dimethyl- and diethylphosphorylated cholinesterases is markedly restricted by the inevitable formation of rather stable phosphoryl oximes (POXs) with high anticholinesterase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ef22d979b25ee44c13a54eb7ad93fb
https://doi.org/10.1007/s002040050648
https://doi.org/10.1007/s002040050648
Effect of human plasma on the reactivation of sarin-inhibited human erythrocyte acetylcholinesterase
Publikováno v:
Archives of Toxicology. 74:21-26
The reactivation of organophosphate-inhibited acetylcholinesterase (AChE) by oximes inevitably results in the formation of highly reactive phosphoryloximes (POX), which are able to re-inhibit the enzyme. In this study, the dependence of POX formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d89b3da89a50569534f07a07deb0aea
https://doi.org/10.1007/s002040050647
https://doi.org/10.1007/s002040050647
Publikováno v:
Zeitschrift f�r Physik A Hadrons and Nuclei. 341:181-190
We suggest to exploit the quantal fluctuation dissipation theorem to construct equations of motion for the second moments around an average solution. For the case of the single particle density we choose the latter to be given by Landau's kinetic equ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76a09b22ed85288d239ddea0d93df0bd
https://doi.org/10.1007/bf01298478
https://doi.org/10.1007/bf01298478
Autor:
Florian Eyer, Norbert Felgenhauer, Franz Worek, Michael Haberkorn, Veronika Meischner, Horst Thiermann, Peter Eyer, D. Kiderlen, Thomas Zilker
Publikováno v:
Toxicological reviews. 22(3)
The mortality rate of suicidal parathion poisoning is particularly high, the onset of fulminant cholinergic signs, and the patients frequently present to the emergency physician with life-threatening symptoms. Despite this uniformity, subsequent clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5bf3c4d5c2290d7d349b6100cc4352
https://pubmed.ncbi.nlm.nih.gov/15181664
https://pubmed.ncbi.nlm.nih.gov/15181664
Aktuelle Empfehlungen zur Diagnostik und Therapie von Vergiftungen mit insektiziden Organophosphaten
Autor:
Thomas Zilker, Florian Eyer, D. Kiderlen, Peter Eyer, H. Thiermann, V. Meischner, Norbert Felgenhauer
Publikováno v:
Intensivmedizin und Notfallmedizin. 41
Suizidal beabsichtigte Organophosphatvergiftungen fuhren durch ubiquitare Hemmung der Cholinesterasen zur „cholinergen Krise“ und bedurfen einer sofort einzuleitenden Therapie. Neben der supportivintensivmedizinischen Behandlung stellt die Magens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77fb80f7cf907fe07d9acb520321f948
https://doi.org/10.1007/s00390-004-0467-7
https://doi.org/10.1007/s00390-004-0467-7
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 288(1-2)
Determination of erythrocyte acetylcholinesterase (AChE) activity is the appropriate tool for the diagnosis of organophosphate exposure and intoxication. The original colorimetric Ellman procedure is disturbed by a high hemoglobin absorption at 412 n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0d497bab8d0c9dffc7b80ad3393158
https://pubmed.ncbi.nlm.nih.gov/10529460
https://pubmed.ncbi.nlm.nih.gov/10529460
Autor:
H. Hofmann, D. Kiderlen
We address the dynamics of damped collective modes in terms of first and second moments. The modes are introduced in a self-consistent fashion with the help of a suitable application of linear response theory. Quantum effects in the fluctuations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f29bbb0c3289c0f0f3f73400e5655c2
http://arxiv.org/abs/nucl-th/9703056
http://arxiv.org/abs/nucl-th/9703056
Autor:
Helmut Hofmann, D. Kiderlen
We reconsider the importance of statistical fluctuations for fission dynamics beyond the saddle in the light of recent evaluations of transport coefficients for average motion. The size of these fluctuations are estimated by means of the Kramers-Ingo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6863c4c2e706d32fcf76f5ce2b2a9f0
Publikováno v:
Intensivmedizin und Notfallmedizin; Jun2004, Vol. 41 Issue 5, p322-330, 9p