Zobrazeno 1 - 10
of 291
pro vyhledávání: '"D. Kersten"'
Autor:
Donghui Yan, Muqing Zhou, Abhinav Adduri, Yihao Zhuang, Mustafa Guler, Sitong Liu, Hyonyoung Shin, Torin Kovach, Gloria Oh, Xiao Liu, Yuting Deng, Xiaofeng Wang, Liu Cao, David H. Sherman, Pamela J. Schultz, Roland D. Kersten, Jason A. Clement, Ashootosh Tripathi, Bahar Behsaz, Hosein Mohimani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Type 1 polyketides are a major class of natural products used as antiviral, antibiotic, antifungal, antiparasitic, immunosuppressive, and antitumor drugs. Analysis of public microbial genomes leads to the discovery of over sixty thousand typ
Externí odkaz:
https://doaj.org/article/2b6d42dae54c43a3a35eb103adacd3a6
Autor:
Sophia R. Meyer, Charles J. Zhang, Max A. Garcia, Megan C. Procario, Sanghee Yoo, Amber L. Jolly, Sumin Kim, Jiho Kim, Kyusuk Baek, Roland D. Kersten, Robert J. Fontana, Jonathan Z. Sexton
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 8, Pp 1045-1053 (2024)
Background and Aims: Drug-induced liver injury (DILI) is a major failure mode in pharmaceutical development. This study aims to address the limitations of existing preclinical models by assessing a high-throughput, microfluidic liver-on-a-chip system
Externí odkaz:
https://doaj.org/article/963eaa0479fe49e390d72984b603c77a
Autor:
Yi-Yuan Lee, Mustafa Guler, Desnor N. Chigumba, Shen Wang, Neel Mittal, Cameron Miller, Benjamin Krummenacher, Haodong Liu, Liu Cao, Aditya Kannan, Keshav Narayan, Samuel T. Slocum, Bryan L. Roth, Alexey Gurevich, Bahar Behsaz, Roland D. Kersten, Hosein Mohimani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Recent analyses of public microbial genomes have found over a million biosynthetic gene clusters, the natural products of the majority of which remain unknown. Additionally, GNPS harbors billions of mass spectra of natural products without k
Externí odkaz:
https://doaj.org/article/d0cd311036a049e799043f3d3049ff80
Publikováno v:
Plants, Vol 12, Iss 12, p 2313 (2023)
Jujube is a nutritious fruit, and is high in vitamin C, fiber, phenolics, flavonoids, nucleotides, and organic acids. It is both an important food and a source of traditional medicine. Metabolomics can reveal metabolic differences between Ziziphus ju
Externí odkaz:
https://doaj.org/article/ec3914bc82884388b70c7e02082b3944
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Copper is an important transition metal cofactor in plant metabolism, which enables diverse biocatalysis in aerobic environments. Multiple classes of plant metalloenzymes evolved and underwent genetic expansions during the evolution of terrestrial pl
Externí odkaz:
https://doaj.org/article/a508360e08a94cfa84e270c833693dee
Autor:
Alan K. Jarmusch, Allegra T. Aron, Daniel Petras, Vanessa V. Phelan, Wout Bittremieux, Deepa D. Acharya, Mohammed M. A. Ahmed, Anelize Bauermeister, Matthew J. Bertin, Paul D. Boudreau, Ricardo M. Borges, Benjamin P. Bowen, Christopher J. Brown, Fernanda O. Chagas, Kenneth D. Clevenger, Mario S. P. Correia, William J. Crandall, Max Crüsemann, Tito Damiani, Oliver Fiehn, Neha Garg, William H Gerwick, Jeffrey R. Gilbert, Daniel Globisch, Paulo Wender P. Gomes, Steffen Heuckeroth, C. Andrew James, Scott A. Jarmusch, Sarvar A. Kakhkhorov, Kyo Bin Kang, Roland D Kersten, Hyunwoo Kim, Riley D. Kirk, Oliver Kohlbacher, Eftychia E. Kontou, Ken Liu, Itzel Lizama-Chamu, Gordon T. Luu, Tal Luzzatto Knaan, Michael T. Marty, Andrew C. McAvoy, Laura-Isobel McCall, Osama G. Mohamed, Omri Nahor, Timo H.J. Niedermeyer, Trent R. Northen, Kirsten E. Overdahl, Tomáš Pluskal, Johannes Rainer, Raphael Reher, Elys Rodriguez, Timo T. Sachsenberg, Laura M. Sanchez, Robin Schmid, Cole Stevens, Zhenyu Tian, Ashootosh Tripathi, Hiroshi Tsugawa, Kozo Nishida, Yuki Matsuzawa, Justin J.J. van der Hooft, Andrea Vicini, Axel Walter, Tilmann Weber, Quanbo Xiong, Tao Xu, Haoqi Nina Zhao, Pieter C. Dorrestein, Mingxun Wang
Even though raw mass spectrometry data is information rich, the vast majority of the data is underutilized. The ability to interrogate these rich datasets is handicapped by the limited capability and flexibility of existing software. We introduce the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8f988ad1b439278436871971e6c216c
https://doi.org/10.1101/2022.08.06.503000
https://doi.org/10.1101/2022.08.06.503000
Publikováno v:
Appl Environ Microbiol
Interactions between bacteria and phytoplankton can influence primary production, community composition, and algal bloom development. However, these interactions are poorly described for many consortia, particularly for freshwater bloom-forming cyano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eee24a071087488ff55a732d7182ddb
https://doi.org/10.1128/aem.01803-21
https://doi.org/10.1128/aem.01803-21
Autor:
Roland D. Kersten, Lisa S. Mydy, Timothy R. Fallon, Floris de Waal, Khadija Shafiq, Jesse W. Wotring, Jonathan Z. Sexton, Jing-Ke Weng
Publikováno v:
Journal of the American Chemical Society. 144(17)
Moroidin is a bicyclic plant octapeptide with tryptophan side-chain cross-links, originally isolated as a pain-causing agent from the Australian stinging tree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48c02b6334b943bf2a194184f22e0b9
https://pubmed.ncbi.nlm.nih.gov/35438481
https://pubmed.ncbi.nlm.nih.gov/35438481
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Frontiers in Plant Science
Frontiers in Plant Science
Copper is an important transition metal cofactor in plant metabolism, which enables diverse biocatalysis in aerobic environments. Multiple classes of plant metalloenzymes evolved and underwent genetic expansions during the evolution of terrestrial pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ec7bef75bf5bba6f704f3373860da0
https://www.frontiersin.org/articles/10.3389/fpls.2021.692108/full
https://www.frontiersin.org/articles/10.3389/fpls.2021.692108/full
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