Zobrazeno 1 - 10
of 72
pro vyhledávání: '"D. Kent Morest"'
Publikováno v:
Developmental Biology. 379:208-220
Sensory and endoneurocrine tissues as diverse as the lens, the olfactory epithelium, the inner ear, the cranial sensory ganglia, and the anterior pituitary arise from a common pool of progenitors in the preplacodal ectoderm (PPE). Around late gastrul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e7ed3798ea3599119693ca69c8f8e5
https://doi.org/10.1016/j.ydbio.2013.04.023
https://doi.org/10.1016/j.ydbio.2013.04.023
Publikováno v:
Otology & Neurotology. 29:1005-1011
Intratympanic (IT) application of dexamethasone will reduce ototoxicity associated with systemic cisplatin therapy.Cisplatin is a common chemotherapeutic drug often dose-limited by ototoxicity attributed to the formation of reactive oxygen and nitrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851e4a2b16bff016ca3b45e6294e6f84
https://doi.org/10.1097/mao.0b013e31818599d5
https://doi.org/10.1097/mao.0b013e31818599d5
Publikováno v:
Journal of Neuroscience Research. 86:2376-2391
A growth factor may have different actions depending on developmental stage. We investigated this phenomenon in the interactions of fibroblast growth factor 2 (FGF2) and neurotrophins on cochlear ganglion (CG) development. The portions of the otocyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054baf1d180abd6191df8263603ce9e5
https://doi.org/10.1002/jnr.21685
https://doi.org/10.1002/jnr.21685
Publikováno v:
European Journal of Neuroscience. 26:666-680
In adult mammals a single exposure to loud noise can damage cochlear hair cells and initiate subsequent episodes of degeneration of axonal endings in the cochlear nucleus (CN). Possible mechanisms are loss of trophic support and/or excitotoxicity. Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e3a86e7fb92aa3a385b098d516da23
https://doi.org/10.1111/j.1460-9568.2007.05695.x
https://doi.org/10.1111/j.1460-9568.2007.05695.x
Autor:
D. Kent Morest, Jane J. Feng
Publikováno v:
Hearing Research. :116-126
The potassium channel protein, Kv3.1, is abundantly expressed in the chick auditory pathway. Its b-isoform is found in nucleus magnocellularis, which receives the cochlear input, both before and after the establishment of synaptic connections. It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8fd6c24dba594e56859010e151931d
https://doi.org/10.1016/j.heares.2006.01.012
https://doi.org/10.1016/j.heares.2006.01.012
Publikováno v:
The Journal of Neuroscience. 25:6857-6868
The origin of the action potential in the cochlea has been a long-standing puzzle. Because voltage-dependent Na+(Nav) channels are essential for action potential generation, we investigated the detailed distribution of Nav1.6 and Nav1.2 in the cochle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fc83464082990a86fe49e0e587ce95
https://doi.org/10.1523/jneurosci.0123-05.2005
https://doi.org/10.1523/jneurosci.0123-05.2005
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2004, 24 (33), pp.7230-7240. ⟨10.1523/JNEUROSCI.2125-04.2004⟩
Journal of Neuroscience, Society for Neuroscience, 2004, 24 (33), pp.7230-7240. ⟨10.1523/JNEUROSCI.2125-04.2004⟩
High densities of sodium channels at nodes of Ranvier permit action potential conduction and depend on βIV spectrins, a family of scaffolding proteins linked to the cortical actin cytoskeleton. To investigate the molecular organization of nodes, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f85ae3a430747853892f94a09fd41f
https://doi.org/10.1523/jneurosci.2125-04.2004
https://doi.org/10.1523/jneurosci.2125-04.2004
Autor:
Jerry Silver, D. Kent Morest
Publikováno v:
Glia. 43:6-18
Neurons, neuroglia (astrocytes and oligodendrocytes), and ependymal cells are three distinct categories of neural cells in the central nervous system. In the mature brain and spinal cord, the classical histological criteria define these cells by thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4272fd23faad405844c2825d85248c
https://doi.org/10.1002/glia.10238
https://doi.org/10.1002/glia.10238
Publikováno v:
Hearing Research. 169:1-12
To see if fibroblast growth factors (FGFs) might function in the central changes following auditory overstimulation we tracked immunostaining in the cochlear nucleus of adult mice with monoclonal antibodies to FGFs (FGF-1, FGF-2) and FGF receptor. Af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696109c6244ca6ebf50920ec2fbe94b5
https://doi.org/10.1016/s0378-5955(02)00461-6
https://doi.org/10.1016/s0378-5955(02)00461-6
