Zobrazeno 1 - 10
of 492
pro vyhledávání: '"D. Kenney"'
Autor:
Samuel Speaks, Matthew I. McFadden, Ashley Zani, Abigail Solstad, Steve Leumi, Jack E. Roettger, Adam D. Kenney, Hannah Bone, Lizhi Zhang, Parker J. Denz, Adrian C. Eddy, Amal O. Amer, Richard T. Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function of the inflammasome-activated, pore-forming protein gasdermin D (GSDMD) during in
Externí odkaz:
https://doaj.org/article/1bdb4d643c5340eaab89b6eb41184ba9
Autor:
O. O’Brien, D. E. Pendleton, L. C. Ganley, K. R. McKenna, R. D. Kenney, E. Quintana-Rizzo, C. A. Mayo, S. D. Kraus, J. V. Redfern
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Climate change is affecting species distributions in space and time. In the Gulf of Maine, one of the fastest-warming marine regions on Earth, rapid warming has caused prey-related changes in the distribution of the critically endangered Nor
Externí odkaz:
https://doaj.org/article/6d2db5d7a59d4234b095f59544f3fd4f
Autor:
Nicholas A. Farmer, Lance P. Garrison, Calusa Horn, Margaret Miller, Timothy Gowan, Robert D. Kenney, Michelle Vukovich, Julia Robinson Willmott, Jessica Pate, D. Harry Webb, Timothy J. Mullican, Joshua D. Stewart, Kim Bassos-Hull, Christian Jones, Delaney Adams, Nicole A. Pelletier, Jordan Waldron, Stephen Kajiura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract In 2018, the giant manta ray was listed as threatened under the U.S. Endangered Species Act. We integrated decades of sightings and survey effort data from multiple sources in a comprehensive species distribution modeling (SDM) framework to
Externí odkaz:
https://doaj.org/article/6a89d34bdb124e788843600a038308e0
Autor:
Matthew D Lettrich, Michael J Asaro, Diane L Borggaard, Dorothy M Dick, Roger B Griffis, Jenny A Litz, Christopher D Orphanides, Debra L Palka, Melissa S Soldevilla, Brian Balmer, Samuel Chavez, Danielle Cholewiak, Diane Claridge, Ruth Y Ewing, Kristi L Fazioli, Dagmar Fertl, Erin M Fougeres, Damon Gannon, Lance Garrison, James Gilbert, Annie Gorgone, Aleta Hohn, Stacey Horstman, Beth Josephson, Robert D Kenney, Jeremy J Kiszka, Katherine Maze-Foley, Wayne McFee, Keith D Mullin, Kimberly Murray, Daniel E Pendleton, Jooke Robbins, Jason J Roberts, Grisel Rodriguez-Ferrer, Errol I Ronje, Patricia E Rosel, Todd Speakman, Joy E Stanistreet, Tara Stevens, Megan Stolen, Reny Tyson Moore, Nicole L Vollmer, Randall Wells, Heidi R Whitehead, Amy Whitt
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0290643 (2023)
Climate change and climate variability are affecting marine mammal species and these impacts are projected to continue in the coming decades. Vulnerability assessments provide a framework for evaluating climate impacts over a broad range of species u
Externí odkaz:
https://doaj.org/article/9340d2451ab241b2a69a5971e91e50b8
Autor:
Guoli Shi, Abhilash I. Chiramel, Tiansheng Li, Kin Kui Lai, Adam D. Kenney, Ashley Zani, Adrian C. Eddy, Saliha Majdoul, Lizhi Zhang, Tirhas Dempsey, Paul A. Beare, Swagata Kar, Jonathan W. Yewdell, Sonja M. Best, Jacob S. Yount, Alex A. Compton
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in immunocompromised individuals is associated with prolonged virus shedding and evolution of viral variants. Rapamycin and its analogs (rapalogs, including everolimus, temsirolim
Externí odkaz:
https://doaj.org/article/54c02ef4c7e14f2d8fd82a8b248817d9
Autor:
Georgios I. Laliotis, Adam D. Kenney, Evangelia Chavdoula, Arturo Orlacchio, Abdul Kaba, Alessandro La Ferlita, Vollter Anastas, Christos Tsatsanis, Joal D. Beane, Lalit Sehgal, Vincenzo Coppola, Jacob S. Yount, Philip N. Tsichlis
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Laliotis et al. examine the role of the AKT3-phoshorylated RNA processing factor IWS1 and the IWS1 phosphorylation-dependent alternative splicing of U2AF2 in lung adenocarcinoma cells. The alternatively spliced variant of U2AF2 regulates the nuclear
Externí odkaz:
https://doaj.org/article/4976aacb26fc469e84b6096ba7b23887
Autor:
Tai-Wei Li, Adam D. Kenney, Jun-Gyu Park, Guillaume N. Fiches, Helu Liu, Dawei Zhou, Ayan Biswas, Weiqiang Zhao, Jianwen Que, Netty Santoso, Luis Martinez-Sobrido, Jacob S. Yount, Jian Zhu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results reveal that the SA
Externí odkaz:
https://doaj.org/article/92359d42839349c18b69b00619ad6b06
Autor:
Colton R Martens, Lisa E Dorn, Adam D Kenney, Shyam S Bansal, Jacob S Yount, Federica Accornero
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010342 (2022)
Viral infection of the heart is a common but underappreciated cause of heart failure. Viruses can cause direct cardiac damage by lysing infected cardiomyocytes. Inflammatory immune responses that limit viral replication can also indirectly cause dama
Externí odkaz:
https://doaj.org/article/8c6a49a89578411b9e205be4566e928a
Autor:
Matthew Sermersheim, Adam D. Kenney, Pei-Hui Lin, Temet M. McMichael, Chuanxi Cai, Kristyn Gumpper, T. M. Ayodele Adesanya, Haichang Li, Xinyu Zhou, Ki-Ho Park, Jacob S. Yount, Jianjie Ma
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.
Externí odkaz:
https://doaj.org/article/6597955c13bc4dd2bb5688a5b442a740
Publikováno v:
Publications of the Astronomical Society of Australia. :1-23
The report of a detection of an absorption profile centred at 78 MHz in the continuum radio background spectrum by the EDGES experiment and its interpretation as the redshifted 21 cm signal of cosmological origin has become one of the most debated re