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pro vyhledávání: '"D. K. Waiting"'
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 33:453-460
Mealey, K.L., Waiting, D., Raunig, D.L., Schmidt, K.R., Nelson, F.R. Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs. J. vet. Pharmacol. Therap. 33, 453–460. Previous studies have indi
Autor:
Russell L. Tucker, G. Roberts, Katrina L. Mealey, D. K. Waiting, John S. Mattoon, J. C. Coelho
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 32:417-421
P-glycoprotein (P-gp), the product of ABCB1 gene, is thought to play a role in the biliary excretion of a variety of drugs, but specific studies in dogs have not been performed. Because a number of endogenous (ABCB1 polymorphisms) and exogenous (phar