Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D. K. Monteith"'
Publikováno v:
Toxicological Sciences. 46:365-375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdfd48200d215f9e97bc3f1db5240c85
https://doi.org/10.1093/toxsci/46.2.365
https://doi.org/10.1093/toxsci/46.2.365
Autor:
Scott P, Henry, D K, Monteith, J E, Matson, B H, Mathison, K S, Loveday, R A, Winegar, P S, Lee, E S, Riccio, J P, Bakke, A A, Levin
Publikováno v:
Mutagenesis. 17(3)
ISIS 2302, a phosphorothioate oligodeoxynucleotide with antisense activity against human ICAM-1 mRNA, was evaluated in a battery of tests to assess genotoxic potential. There was no evidence of genotoxicity in three in vitro studies performed: (i) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695ede935cacf398a51e64c1289857b2
https://pubmed.ncbi.nlm.nih.gov/11971990
https://pubmed.ncbi.nlm.nih.gov/11971990
Autor:
M J, Graham, S T, Crooke, D K, Monteith, S R, Cooper, K M, Lemonidis, K K, Stecker, M J, Martin, R M, Crooke
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(1)
In the rat, the liver represents a major site of phosphorothioate oligodeoxynucleotide deposition after i.v. administration. For this reason, we examined the intracellular fate of ISIS 1082, a 21-base heterosequence phosphorothioate oligodeoxynucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eee0651e48813e3c63e5bf3b2ca8a27a
https://pubmed.ncbi.nlm.nih.gov/9655890
https://pubmed.ncbi.nlm.nih.gov/9655890
Publikováno v:
Anti-cancer drug design. 12(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19ec353bac04829adfb9af923ac2767c
https://pubmed.ncbi.nlm.nih.gov/9236854
https://pubmed.ncbi.nlm.nih.gov/9236854
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642646577
Alzheimer’s disease (AD) is a clinically debilitating dementia associated with various stages of memory dysfunction leading ultimately over a period of years to death. Extensive research is ongoing to determine the underlying etiology of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b04e0cbbb136641c9e784e3c8f8c29c
https://doi.org/10.1007/978-3-642-61013-4_17
https://doi.org/10.1007/978-3-642-61013-4_17
Publikováno v:
Drug and chemical toxicology. 19(1-2)
Tacrine is the first drug approved for the treatment of Alzheimer's disease. Approximately 50% of patients treated with tacrine develop elevated serum aminotransferase levels, as an indication of potential hepatotoxicity. However, acute and chronic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aea98b82013a09e03bbfd0de70709a
https://pubmed.ncbi.nlm.nih.gov/8804554
https://pubmed.ncbi.nlm.nih.gov/8804554
Autor:
J. C. Theiss, D. K. Monteith
Publikováno v:
Drug and chemical toxicology. 19(1-2)
Tacrine is the first drug approved for the treatment of Alzheimer's disease. Approximately 50% of patients treated with tacrine develop elevated serum aminotransferase levels, an indication of potential hepatotoxicity. The mechanism of human hepatoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869319ae648968aa8df77a662eace7d8
https://pubmed.ncbi.nlm.nih.gov/8804553
https://pubmed.ncbi.nlm.nih.gov/8804553
Autor:
J A, Benvenuto, T H, Connor, D K, Monteith, J L, Laidlaw, S C, Adams, T S, Matney, J C, Theiss
Publikováno v:
Journal of pharmaceutical sciences. 82(10)
Chemical methods for the degradation of 11 antineoplastic drugs [etoposide, teniposide, bleomycin, mitomycin C, cisplatin, cis-dichloro-trans-dihydroxy-bis(isopropylamine) platinum IV (CHIP), cyclophosphamide, ifosfamide, carmustine, lomustine, and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75e8307cec1df16dc7127e4098ce7860
https://pubmed.ncbi.nlm.nih.gov/8254498
https://pubmed.ncbi.nlm.nih.gov/8254498
Publikováno v:
Toxicology Letters. 40:257-268
A concern among hospital personnel is their exposure to mutagenic drugs and in the incidental exposures that could occur in caring for the patients. In a recent published study the mutagenicity of urine from patients administered antineoplastic drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5782288abb853b5ad7e7f030e52ab099
https://doi.org/10.1016/0378-4274(88)90049-5
https://doi.org/10.1016/0378-4274(88)90049-5