Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D. K. Manchester"'
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 62:93-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9086edd7c7e08bd2b2dc3dce6345322
https://doi.org/10.1007/s001289900846
https://doi.org/10.1007/s001289900846
Autor:
J M, Wong, P A, Harper, U A, Meyer, K W, Bock, K, Morike, J, Lagueux, P, Ayotte, R F, Tyndale, E M, Sellers, D K, Manchester, A B, Okey
Publikováno v:
Pharmacogenetics. 11(1)
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcriptional regulator of several genes including the cytochrome P4501 (CYP1) family as well as genes encoding factors involved in cell growth and differentiation. In mice, several polymorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c152dd70f5a62a99cea217eccc7a9a5
https://pubmed.ncbi.nlm.nih.gov/11207035
https://pubmed.ncbi.nlm.nih.gov/11207035
Publikováno v:
American journal of medical genetics. 62(4)
Hunter-McAlpine syndrome is an autosomal dominant disorder consisting of variable manifestations including craniosynostosis, almond-shaped palpebral fissures, small mouth, mild acral-skeletal anomalies, short stature, and mental deficiency. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c9c44eb55922a20a6ca645ba56c80da
https://pubmed.ncbi.nlm.nih.gov/8723067
https://pubmed.ncbi.nlm.nih.gov/8723067
Publikováno v:
American journal of human genetics. 53(1)
Ehlers-Danlos syndrome (EDS) type IV is a dominantly inherited disorder that results from mutations in the type III collagen gene (COL3A1). We studied the structure of the COL3A1 gene of an individual with EDS type IV and that of her phenotypically n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::589914454ef26dfdd21e100905a1e8c9
https://pubmed.ncbi.nlm.nih.gov/8317500
https://pubmed.ncbi.nlm.nih.gov/8317500
Publikováno v:
Cancer research. 52(6)
To determine the relative contributions of tobacco smoking and P-450 metabolism (cytochrome P-450IAI) in the formation of benzo(a)pyrenediol-epoxide and other polycyclic aromatic hydrocarbon-DNA adducts in vivo, 16 human placentas were assayed for ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48d9f0f7cb2e2233e6ceecf0f1c4d50e
https://pubmed.ncbi.nlm.nih.gov/1540958
https://pubmed.ncbi.nlm.nih.gov/1540958
Publikováno v:
Basic life sciences. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a469fe384a86834e1a33ec0b3b0b73e6
https://pubmed.ncbi.nlm.nih.gov/2126432
https://pubmed.ncbi.nlm.nih.gov/2126432
Publikováno v:
Journal of the American College of Toxicology. 8:913-932
A major concern of molecular epidemiology is the identification of individuals at increased risk of cancer by obtaining evidence of high exposure to carcinogens that may lead to pathobiological lesions in target cells. DNA is considered to be a targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::657754c6d63391361c138d29338a2f5f
https://doi.org/10.3109/10915818909018052
https://doi.org/10.3109/10915818909018052
Autor:
T, Fujino, K, Gottlieb, D K, Manchester, S S, Park, D, West, H L, Gurtoo, R E, Tarone, H V, Gelboin
Publikováno v:
Cancer research. 44(9)
Cytochromes P-450 are a family of enzymes responsible for metabolism of drug and xenobiotics, such as carcinogen, and certain physiological compounds, such as steroids and prostaglandins. We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f7ec0b5d88208408aa49e819345b626
https://pubmed.ncbi.nlm.nih.gov/6611202
https://pubmed.ncbi.nlm.nih.gov/6611202
Autor:
A, Weston, J C, Willey, D K, Manchester, V L, Wilson, B R, Brooks, J S, Choi, M C, Poirier, G E, Trivers, M J, Newman, D L, Mann
Publikováno v:
IARC scientific publications. (89)
The metabolic activation of polycyclic aromatic hydrocarbons (PAH), for example benzo[a]pyrene, leads to the formation of carcinogen-macromolecular adducts. Methods that make it possible to detect low levels of these adducts in human peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d408a2aeff322acb313503bb8f4f6602
https://pubmed.ncbi.nlm.nih.gov/3143667
https://pubmed.ncbi.nlm.nih.gov/3143667
Publikováno v:
Seminars in perinatology. 9(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0311f1f8f29b42c82a3abe6f64068a3a
https://pubmed.ncbi.nlm.nih.gov/4035390
https://pubmed.ncbi.nlm.nih.gov/4035390