Zobrazeno 1 - 10
of 47
pro vyhledávání: '"D. K. Dube"'
Autor:
F, Meng, X P, Huang, C, Zhang, R W, Zajdel, D, Foster, N, Dawson, S L, Lemanski, D, Zawieja, D K, Dube, L F, Lemanski
Publikováno v:
Tissuecell. 35(2)
The axolotl, Ambystoma mexicanum , is a useful system for studying embryogenesis and cardiogenesis. To understand the role of protein tyrosine phosphorylation during heart development in normal and cardiac mutant axolotl embryonic hearts, we have inv
Autor:
R W, Zajdel, M D, McLean, S L, Lemanski, M, Muthuchamy, D F, Wieczorek, L F, Lemanski, D K, Dube
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 213(4)
Expression of tropomyosin protein, an essential component of the thin filament, has been found to be drastically reduced in cardiac mutant hearts of the Mexican axolotl (Ambystoma mexicanum) with no formation of sarcomeric myofibrils. Therefore, this
Autor:
L F, Lemanski, R W, Zajdel, M, Nakasugawa, R, Bhatia, B J, Spinner, M E, Fransen, A F, Gaur, M D, McLean, S L, Lemanski, D K, Dube
Publikováno v:
Tsitologiia. 39(10)
Publikováno v:
Biochemistry and molecular biology international. 38(6)
We have isolated and sequenced a full-length (0.9 kb) cDNA clone of ribosomal protein S3 by subtraction hybridization using a single-stranded cDNA library from stage 25-27 (tracer) and the mRNA from stage 15-17 (driver) of embryonic Mexican axolotl (
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 205(2)
Regulated assembly of contractile proteins into sarcomeric structures, such as A- and I-bands, is still currently being defined. The presence of distinct isoforms of several muscle proteins suggests a possible mechanism by which myocytes regulate ass
Publikováno v:
Biochemistry and molecular biology international. 38(1)
In this study, we have cloned a 1.0 kb myosin heavy chain (MHC) cDNA by screening an axolotl heart cDNA library with the monoclonal antibody MF20 against a light meromyosin (LMM) region of MHC. The nucleotide sequence analysis shows 85-86% homology a
Publikováno v:
Biochemical and biophysical research communications. 213(1)
C-protein, a myosin binding protein, is thought to regulate and stabilize thick filaments during assembly of sarcomeric A-bands. Multiple isoforms of C-protein have been characterized in avian and mammalian systems. We now report the isolation and th
Publikováno v:
Cellularmolecular biology research. 41(2)
Recessive mutant gene c for "'cardiac nonfunction" in the mexican axolotl, Ambystoma mexicanum, results in a failure of affected embryos to develop contracting hearts. Mutant embryos survive approximately 4 weeks after fertilization, but eventually d
Autor:
M P, Sherman, S, Dube, T P, Spicer, T D, Kane, J L, Love, N K, Saksena, R, Iannone, C J, Gibbs, R, Yanagihara, D K, Dube
Publikováno v:
Cancer research. 53(24)
Human T-cell lymphoma/leukemia virus type I (HTLV-I) causes adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy. Specific regions within the outer envelope proteins of other retroviruses, e.g., human immunodeficiency virus type 1, are hig
Autor:
S M, LaFrance, M E, Fransen, N, Erginel-Unaltuna, D K, Dube, D R, Robertson, C, Stefanu, T K, Ray, L F, Lemanski
Publikováno v:
Cellularmolecular biology research. 39(6)
In the axolotl, Ambystoma mexicanum, a recessive cardiac lethal mutation causes an incomplete differentiation of the myocardium. Mutant hearts do not contain sarcomeric myofibrils nor do they beat. We have previously shown that normal anterior endode