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pro vyhledávání: '"D. K., Galanakis"'
Publikováno v:
Thrombosis and haemostasis. 83(4)
Because it contains three pairs of polypeptides, fibrinogen isolated from heterozygous individuals is expected to be a mixture of homodimers and heterodimers. Nevertheless, heterozygous individuals with only homodimers have been identified. We synthe
Publikováno v:
Blood. 90(7)
Fib420 is a recently identified subclass of normal human fibrinogen in which two extended alpha chain isoforms (alphaE) replace the common alpha chains, yielding a molecule (ca. 420 kD) which is larger than the more abundant 340-kD form. Evidence for
Autor:
D. K. Galanakis, E. I. B. Peerschke
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 7(3)
Evidence is emerging for the regulation of platelet function at sites of vascular injury or thrombosis by multiple platelet recognition sites in fibrinogen. This study examined the interaction of platelets with immobilized fibrinogen degradation prod
Autor:
B, Ghebrehiwet, D K, Galanakis
Publikováno v:
Behring Institute Mitteilungen. (93)
The serum C1q inhibitor (C1q INH) is a chondroitin 4-sulfate proteoglycan which is composed of several polyanionic components ranging in size from 21-750 kDa. Although the activity of C1q INH has been described in terms of its ability to precipitate
Autor:
D K, Galanakis
Publikováno v:
Hematology/oncology clinics of North America. 6(5)
The precipitous increase in the number of structurally defined fibrinogen defects in recent years has resulted from application of high performance liquid chromatography in combination with peptide mapping and sequencing procedures. More recently, ap
Autor:
D K, Galanakis, M, Hultin
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 1(4-5)
We describe preliminary studies of a new familial dysfibrinogen, fibrinogen Stony Brook II, present in a propositus and his mother. Both presented with a history of unexplained and chronic joint swelling following trauma, and the propositus suffered
Publikováno v:
Blood. 52:1037-1046
There is paucity of information regarding the prolonged plasma thrombin time known to occur in some patients with systemic lupus erythematosus. Detailed investigations of plasma from two such patients disclosed that IgG accounted for this defect in e
Autor:
A. Henschen, D. K. Galanakis
Publikováno v:
Structural variants and interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67d2c0309fb5273f87a0613c2972df1
https://doi.org/10.1515/9783110855951-021
https://doi.org/10.1515/9783110855951-021
Publikováno v:
Annals of clinical and laboratory science. 9(5)
Two new commercial assays for the detection of degradation products of fibrinogen/fibrin (FDP) were evaluated against two standard procedures. The first, a new hemagglutination inhibition (HAI) assay using glutaraldehyde-treated cells, was compared w
Autor:
E I, Peerschke, D K, Galanakis
Publikováno v:
The Journal of laboratory and clinical medicine. 101(3)
Fibrinogen supports platelet aggregation by binding to specific receptors. The importance of the fibrinogen A alpha chain in this hemostatic function is controversial. We found that fibrinogen derivatives, isolated from plasma or obtained after limit