Zobrazeno 1 - 10
of 46
pro vyhledávání: '"D. Jean White"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293:R1684-R1692
Cardiomyocyte sodium accumulation after burn injury precedes the development of myocardial contractile dysfunction. The present study examined the effects of burn injury on Na-K-ATPase activity in adult rat hearts after major burn injury and explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659b446c8ee9aaa0149d232f9d3857ec
https://doi.org/10.1152/ajpregu.00219.2007
https://doi.org/10.1152/ajpregu.00219.2007
Publikováno v:
Journal of Applied Physiology. 102:2207-2216
We proposed that selective decontamination of the digestive tract (SDD) initiated after experimental burn injury would decrease myocardial inflammation and dysfunction after a second insult such as septic challenge. Rats were divided into eight exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb10d192dfb6bb282982f6c0a08c208
https://doi.org/10.1152/japplphysiol.01365.2005
https://doi.org/10.1152/japplphysiol.01365.2005
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H2779-H2789
This study examined the effects of antioxidant vitamins on several aspects of sepsis-related myocardial signaling cascades. Sprague-Dawley rats were divided into four groups: group 1, vehicle-treated shams; group 2, sham-operated rats given antioxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd3cddaad169511772834f59c7df500
https://doi.org/10.1152/ajpheart.01258.2005
https://doi.org/10.1152/ajpheart.01258.2005
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H1642-H1650
The present study examined the hypothesis that hypertonic saline dextran (HSD), given after an initial insult, attenuates exaggerated inflammation that occurs with a second insult. Adult rats ( n = 15 per group) were divided into groups 1 (sham burn)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cdd97d72256a00ba873a4a0dc8b1c9
https://doi.org/10.1152/ajpheart.00586.2005
https://doi.org/10.1152/ajpheart.00586.2005
Publikováno v:
Critical Care Medicine. 33:1021-1028
Sepsis-induced cardiac dysfunction is a serious clinical syndrome characterized by hypotension, decreased systemic vascular resistance, and elevated cardiac index. Although cytokines such as tumor necrosis factor (TNF)-alpha have been shown to play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99632a3bfc7164519230031beab9dda0
https://doi.org/10.1097/01.ccm.0000163398.79679.66
https://doi.org/10.1097/01.ccm.0000163398.79679.66
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H744-H751
This study was designed to examine the role of mitochondrial Ca2+homeostasis in burn-related myocardial inflammation. We hypothesized that mitochondrial Ca2+is a primary modulator of cardiomyocyte TNF-α, IL-1β, and IL-6 responses to injury and infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df446b7d67675b31c2c0eac19d71abd5
https://doi.org/10.1152/ajpheart.00367.2004
https://doi.org/10.1152/ajpheart.00367.2004
Autor:
D. Jean White, Roger A. Schultz, J. Victor Garcia, Brian W. Binck, Jureta W. Horton, May F. Tsen, Miguel Islas, Monte S. Willis, James A. Thomas
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H577-H583
How infection precipitates depressed contractility is incompletely understood but may involve the immune, nervous, and endocrine systems as well as the heart itself. In this study, we examined the role of Toll-like receptor 4 (TLR4) in LPS-induced my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf16f2ff49c6f177c048ea6fece04a6
https://doi.org/10.1152/ajpheart.00745.2004
https://doi.org/10.1152/ajpheart.00745.2004
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H2241-H2251
This study examined the effects of oral antibiotics to selectively decontaminate the digestive tract (SDD) on postburn myocardial signaling, inflammation, and function. We hypothesized that antibiotic therapy to eliminate pathogens from the gastroint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bb90ed7858e4da26234a151f2e0fca
https://doi.org/10.1152/ajpheart.00390.2004
https://doi.org/10.1152/ajpheart.00390.2004
Publikováno v:
Shock. 22:438-445
Large cutaneous burns are clearly recognized to produce acute myocardial contractile dysfunction. This study used a model of burn serum challenge in either primary cardiomyocyte cultures or isolated perfused hearts to examine several aspects of burn-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65c32b1e4432fb8f4fa64e98b3122ee
https://doi.org/10.1097/01.shk.0000142252.31006.c5
https://doi.org/10.1097/01.shk.0000142252.31006.c5
Publikováno v:
Critical Care Medicine. 32:1338-1345
OBJECTIVE This study was designed to determine whether cutaneous burn injury up-regulated expression of myocardial heat shock protein (HSP)70 and to determine a potential cardioprotective role of inducible HSP70 (iHSP70) in postburn myocardial contra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24b22645442be0fb511778e6e3a4b13
https://doi.org/10.1097/01.ccm.0000128571.39037.09
https://doi.org/10.1097/01.ccm.0000128571.39037.09