Zobrazeno 1 - 10
of 198
pro vyhledávání: '"D. Jacobson-Kram"'
Autor:
Peter Kasper, David Kirkland, Yoshifumi Uno, D. Jacobson-Kram, M. Hayashi, James T. MacGregor, Lutz Müller
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 627:5-9
Publikováno v:
Environmental and Molecular Mutagenesis. 27:152-161
The oxime HI-6 dichloride (1-(2 hydroxyiminomethyl- 1-pyridino)-3- (4-carbamoyl-1- pyridino)-2-oxapropane dichloride monohydrate) has shown to be a potent reactivator of cholinesterase activity and may have efficacy for the treatment of organo-phosph
Autor:
D. Jacobson-Kram
Publikováno v:
Veterinary pathology. 45(5)
Much attention and angst have been focused on the decline in new drug approvals, the increased failure rate of drug candidates in late stage development, and the soaring costs of developing new drugs. The causes for this crisis have been much discuss
Publikováno v:
Environmental and molecular mutagenesis. 37(1)
Genomic DNA was isolated from subcutaneous masses observed in CD-1 and p53+/- heterozygous mice during the course of carcinogenicity studies in the vehicle control groups. These masses resulted after daily subcutaneous injection of an antioxidant veh
Autor:
D, Gulezian, D, Jacobson-Kram, C B, McCullough, H, Olson, L, Recio, D, Robinson, R, Storer, R, Tennant, J M, Ward, D A, Neumann
Publikováno v:
Toxicologic pathology. 28(3)
Advances in genetic engineering have created opportunities for improved understanding of the molecular basis of carcinogenesis. Through selective introduction, activation, and inactivation of specific genes, investigators can produce mice of unique g
Autor:
M C, Poirier, A, Weston, B, Schoket, H, Shamkhani, C F, Pan, M A, McDiarmid, B G, Scott, D P, Deeter, J M, Heller, D, Jacobson-Kram, N, Rothman
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 7(6)
Biomarkers of polycyclic aromatic hydrocarbon (PAH) exposure and genetic biomarkers of potential cancer susceptibility were determined in a group of United States Army soldiers who were deployed to Kuwait and Saudi Arabia in 1991 in the aftermath of
Akademický článek
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Publikováno v:
Environmental and molecular mutagenesis. 27(2)
The oxime HI-6 dichloride [1-(2 hydroxyiminomethyl -1-pyridino)-3-(4-carbamoyl-1-pyridino)-2-oxapropane dichloride monohydrate] has shown to be a potent reactivator of cholinesterase activity and may have efficacy for the treatment of organophosphate
Publikováno v:
Journal of applied toxicology : JAT. 13(4)
The mutagenic potential of zinc pyrithione (Znpt) was evaluated in vitro in the Salmonella/mammalian microsome plate incorporation mutagenicity (Ames) assay and the CHO/HGPRT gene mutation assay. The clastogenic potential of Znpt was evaluated in viv
Akademický článek
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