Zobrazeno 1 - 10
of 132
pro vyhledávání: '"D. J. Triggle"'
Autor:
D J, Triggle
Publikováno v:
Pharmaceutica Acta Helvetiae. 74:287-290
Pharmacological receptors are typically defined by their selectivity of ligand recognition, including where appropriate stereoselectivity of interaction. It is increasingly clear that receptors may, in fact, be promiscuous species. This promiscuity a
Publikováno v:
ChemInform. 22
Autor:
S. D. Jablonski, P. Singh, Philip Abraham, J. B. Pitner, Y. W. Kwon, Frank I. Carroll, D. J. Triggle
Publikováno v:
ChemInform. 23
Publikováno v:
Cleveland Clinic Journal of Medicine. 59:617-627
The calcium-channel antagonists represent three separate structural categories of drugs. They share a common action--the blockade of calcium-ion flow through one specific type of calcium channel. The chemical heterogeneity of these agents is reflecte
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H1979-H1987
To examine the status of ATP-sensitive K+ (K+ATP) channels and 1,4-dihydropyridine-sensitive Ca2+ (Ca2+DHP) channels during experimental cardiac failure, we have measured the radioligand binding properties of [3H]glyburide and [3H]PN 200 110, respect
Publikováno v:
Journal of Medicinal Chemistry. 34:3164-3171
Synthesis, radioligand binding, and pharmacologic activities of a series of muscarinic receptor ligands including and related to azaprophen (6-methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate, 1) have been measured to determine activ
Autor:
D J, Triggle
Publikováno v:
IDrugs : the investigational drugs journal. 2(11)
Autor:
D P, Rotella, D J, Triggle
Publikováno v:
IDrugs : the investigational drugs journal. 3(11)
Publikováno v:
Biochemical pharmacology. 62(7)
Binding of the class III antiarrhythmic agent azimilide to brain, heart, and other organ receptors was assessed by standard radioligand binding techniques. In a survey of 60 receptors, azimilide at 10 microM inhibited binding by more than 50% at sero
Autor:
P, Angeli, D J, Triggle
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 55(1)